Advances in the in Vivo Raman Spectroscopy of Malignant Skin Tumors Using Portable Instrumentation
AbstractRaman spectroscopy has emerged as a promising tool for real-time clinical diagnosis of malignant skin tumors offering a number of potential advantages: it is non-intrusive, it requires no sample preparation, and it features high chemical specificity with minimal water interference. However, in vivo tissue evaluation and accurate histopathological classification remain a challenging task for the successful transition from laboratory prototypes to clinical devices. In the literature, there are numerous reports on the applications of Raman spectroscopy to biomedical research and cancer diagnostics. Nevertheless, cases where real-time, portable instrumentations have been employed for the in vivo evaluation of skin lesions are scarce, despite their advantages in use as medical devices in the clinical setting. This paper reviews the advances in real-time Raman spectroscopy for the in vivo characterization of common skin lesions. The translational momentum of Raman spectroscopy towards the clinical practice is revealed by (i) assembling the technical specifications of portable systems and (ii) analyzing the spectral characteristics of in vivo measurements. View Full-Text
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Kourkoumelis, N.; Balatsoukas, I.; Moulia, V.; Elka, A.; Gaitanis, G.; Bassukas, I.D. Advances in the in Vivo Raman Spectroscopy of Malignant Skin Tumors Using Portable Instrumentation. Int. J. Mol. Sci. 2015, 16, 14554-14570.
Kourkoumelis N, Balatsoukas I, Moulia V, Elka A, Gaitanis G, Bassukas ID. Advances in the in Vivo Raman Spectroscopy of Malignant Skin Tumors Using Portable Instrumentation. International Journal of Molecular Sciences. 2015; 16(7):14554-14570.Chicago/Turabian Style
Kourkoumelis, Nikolaos; Balatsoukas, Ioannis; Moulia, Violetta; Elka, Aspasia; Gaitanis, Georgios; Bassukas, Ioannis D. 2015. "Advances in the in Vivo Raman Spectroscopy of Malignant Skin Tumors Using Portable Instrumentation." Int. J. Mol. Sci. 16, no. 7: 14554-14570.