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Int. J. Mol. Sci. 2015, 16(6), 13322-13338; doi:10.3390/ijms160613322

Circulating Long Noncoding RNA as a Potential Target for Prostate Cancer

1
Trainee Brigade, the Third Military Medical University, Chongqing 400038, China
2
Department of Cell Biology, the Third Military Medical University, Chongqing 400038, China
*
Author to whom correspondence should be addressed.
Academic Editor: William Chi-shing Cho
Received: 27 March 2015 / Revised: 1 June 2015 / Accepted: 2 June 2015 / Published: 11 June 2015
(This article belongs to the Special Issue Molecular Classification of Human Cancer: Diagnosis and Treatment)
View Full-Text   |   Download PDF [695 KB, uploaded 11 June 2015]

Abstract

Prostate cancer is considered the second most common visceral malignancy in men in Western countries. Its emergence is largely due to the coordination of a malignant network, and long noncoding RNA has been recently demonstrated to play a critical role in prostate carcinogenesis. The aberrant expression of long noncoding RNA in prostate cancer patients is strongly associated with diagnosis, risk stratification and carcinogenesis, information that provides new insight into the complicated intracellular milieu of prostate cancer. This review focuses mainly on literature evidence for the role of long noncoding RNA in prostate cancer, which may suggest novel strategies for its prognosis, diagnosis and clinical treatment. View Full-Text
Keywords: long noncoding RNA; prostate cancer; biomarker; therapeutic target long noncoding RNA; prostate cancer; biomarker; therapeutic target
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Su, Y.-J.; Yu, J.; Huang, Y.-Q.; Yang, J. Circulating Long Noncoding RNA as a Potential Target for Prostate Cancer. Int. J. Mol. Sci. 2015, 16, 13322-13338.

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