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Int. J. Mol. Sci. 2015, 16(3), 5779-5788; doi:10.3390/ijms16035779

Biomechanical Evaluation of Ti-Nb-Sn Alloy Implants with a Low Young’s Modulus

1
Division of Advanced Prosthetic Dentistry, Tohoku University Graduate School of Dentistry, Tohoku University, 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8577, Japan
2
Division of Community Oral Health Science, Department of Community Medical Supports, Tohoku Medical Megabank Organization, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8573, Japan
3
Division of Craniofacial Function Engineering, Tohoku University Graduate School of Dentistry, Tohoku University, 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8577, Japan
4
Frontier Research Institute for Interdisciplinary Sciences, Tohoku University, Aramaki aza Aoba 6-3, Aoba-ku, Sendai 980-8578, Japan
*
Author to whom correspondence should be addressed.
Academic Editor: Bing Yan
Received: 25 November 2014 / Revised: 9 February 2015 / Accepted: 4 March 2015 / Published: 12 March 2015
(This article belongs to the Special Issue Biomaterials for Tissue Engineering)
View Full-Text   |   Download PDF [1680 KB, uploaded 12 March 2015]   |  

Abstract

Dental implants are widely used and are a predictable treatment in various edentulous cases. Occlusal overload may be causally related to implant bone loss and a loss of integration. Stress concentrations may be diminished using a mechanobiologically integrated implant with bone tissue. The purpose of this study was to investigate the biomechanical behavior, biocompatibility and bioactivity of a Ti-Nb-Sn alloy as a dental implant material. It was compared with cpTi. Cell proliferation and alkaline phosphatase (ALP) activity were quantified. To assess the degree of osseointegration, a push-in test was carried out. Cell proliferation and ALP activity in the cells grown on prepared surfaces were similar for the Ti-Nb-Sn alloy and for cpTi in all the experiments. A comparison between the Ti-Nb-Sn alloy implant and the cpTi implant revealed that no significant difference was apparent for the push-in test values. These results suggest that implants fabricated using Ti-Nb-Sn have a similar biological potential as cpTi and are capable of excellent osseointegration. View Full-Text
Keywords: low Young’s modulus; Ti-Nb-Sn alloy; implant low Young’s modulus; Ti-Nb-Sn alloy; implant
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Takahashi, K.; Shiraishi, N.; Ishiko-Uzuka, R.; Anada, T.; Suzuki, O.; Masumoto, H.; Sasaki, K. Biomechanical Evaluation of Ti-Nb-Sn Alloy Implants with a Low Young’s Modulus. Int. J. Mol. Sci. 2015, 16, 5779-5788.

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