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Int. J. Mol. Sci. 2014, 15(6), 10806-10820; doi:10.3390/ijms150610806
Article

Metabolic Profiling of Somatic Tissues from Monochamus alternatus (Coleoptera: Cerambycidae) Reveals Effects of Irradiation on Metabolism

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Received: 12 May 2014; in revised form: 9 June 2014 / Accepted: 10 June 2014 / Published: 16 June 2014
(This article belongs to the Section Biochemistry, Molecular Biology and Biophysics)
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Abstract: A high-level of sexual sterility is of importance for the sterile insect technique (SIT). However, the use of high-dose-intensity gamma radiation to induce sterility has negative impacts not only on reproductive cells but also on somatic cells. In this study, we investigated the metabolite differences in somatic tissues between non-irradiated, 20-Gy-irradiated, and 40-Gy-irradiated male Monochamus alternatus, an important vector of the pathogenic nematode, Bursaphelenchus xylophilus, which kills Asian pines. The results showed that metabolite levels changed moderately in the 20-Gy samples but were markedly altered in the 40-Gy samples compared with the non-irradiated samples. Twenty-six and 53 metabolites were disturbed by 20-Gy and 40-Gy radiation, respectively. Thirty-six metabolites were found to be markedly altered in the 40-Gy samples but were not changed significantly in the 20-Gy samples. The comprehensive metabolomic disorders induced by 40-Gy radiation dysregulated six metabolic pathways involved in the life process. The findings presented in this manuscript will contribute to our knowledge of the characteristic metabolic changes associated with gamma-radiation-induced damage to somatic cells and will allow for better exploration of the SIT for the control of this target pest.
Keywords: Monochamus alternatus; somatic cells; radiation; metabolomics Monochamus alternatus; somatic cells; radiation; metabolomics
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Qu, L.; Wang, L.; Wang, Q.; Wang, Y.; Zhang, Y. Metabolic Profiling of Somatic Tissues from Monochamus alternatus (Coleoptera: Cerambycidae) Reveals Effects of Irradiation on Metabolism. Int. J. Mol. Sci. 2014, 15, 10806-10820.

AMA Style

Qu L, Wang L, Wang Q, Wang Y, Zhang Y. Metabolic Profiling of Somatic Tissues from Monochamus alternatus (Coleoptera: Cerambycidae) Reveals Effects of Irradiation on Metabolism. International Journal of Molecular Sciences. 2014; 15(6):10806-10820.

Chicago/Turabian Style

Qu, Liangjian; Wang, Lijuan; Wang, Qinghua; Wang, Yuzhu; Zhang, Yongan. 2014. "Metabolic Profiling of Somatic Tissues from Monochamus alternatus (Coleoptera: Cerambycidae) Reveals Effects of Irradiation on Metabolism." Int. J. Mol. Sci. 15, no. 6: 10806-10820.



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