Next Article in Journal
The Canonical Notch Signaling Was Involved in the Regulation of Intestinal Epithelial Cells Apoptosis after Intestinal Ischemia/Reperfusion Injury
Next Article in Special Issue
Functional Annotation of Proteomic Data from Chicken Heterophils and Macrophages Induced by Carbon Nanotube Exposure
Previous Article in Journal
Alpha-Bulges in G Protein-Coupled Receptors
Previous Article in Special Issue
Functional Identification of Proteus mirabilis eptC Gene Encoding a Core Lipopolysaccharide Phosphoethanolamine Transferase
Article Menu

Export Article

Open AccessReview
Int. J. Mol. Sci. 2014, 15(5), 7865-7882; doi:10.3390/ijms15057865

Biomarkers in Alzheimer’s Disease Analysis by Mass Spectrometry-Based Proteomics

School of Life Science, Beijing Institute of Technology, No. 5 Zhongguancun South Street, Haidian District, Beijing 100081, China
These authors contributed equally to this work.
Author to whom correspondence should be addressed.
Received: 19 March 2014 / Revised: 3 April 2014 / Accepted: 9 April 2014 / Published: 6 May 2014
(This article belongs to the Collection Advances in Proteomic Research)
View Full-Text   |   Download PDF [835 KB, uploaded 19 June 2014]   |  


Alzheimer’s disease (AD) is a common chronic and destructive disease. The early diagnosis of AD is difficult, thus the need for clinically applicable biomarkers development is growing rapidly. There are many methods to biomarker discovery and identification. In this review, we aim to summarize Mass spectrometry (MS)-based proteomics studies on AD and discuss thoroughly the methods to identify candidate biomarkers in cerebrospinal fluid (CSF) and blood. This review will also discuss the potential research areas on biomarkers. View Full-Text
Keywords: biomarker; Alzheimer’s disease; mass spectrometry; proteomics biomarker; Alzheimer’s disease; mass spectrometry; proteomics

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Liu, Y.; Qing, H.; Deng, Y. Biomarkers in Alzheimer’s Disease Analysis by Mass Spectrometry-Based Proteomics. Int. J. Mol. Sci. 2014, 15, 7865-7882.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top