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Int. J. Mol. Sci. 2013, 14(9), 18925-18958; doi:10.3390/ijms140918925

The Clinical Utilization of Circulating Cell Free DNA (CCFDNA) in Blood of Cancer Patients

1
Division of Cancer Research and Training, Department of Internal Medicine, Charles Drew University of Medicine and Science, 1720 East 120th Street, Los Angeles, CA 90059, USA
2
Laboratory Diagnostic Medicine, Faculty of Pharmacy, Mazzeh (17th April Street), Damascus University, Damascus, Syria
3
David Geffen School of Medicine at UCLA, UCLA's Jonsson Comprehensive Cancer Center, 8-684 Factor Building, Box 951781, Los Angeles, CA 90095-1781, USA
These authors contributed equally to this work.
*
Author to whom correspondence should be addressed.
Received: 4 June 2013 / Revised: 26 August 2013 / Accepted: 30 August 2013 / Published: 13 September 2013
(This article belongs to the Special Issue Advances in Cancer Diagnosis)
View Full-Text   |   Download PDF [297 KB, uploaded 19 June 2014]

Abstract

Qualitative and quantitative testing of circulating cell free DNA (CCFDNA) can be applied for the management of malignant and benign neoplasms. Detecting circulating DNA in cancer patients may help develop a DNA profile for early stage diagnosis in malignancies. The technical issues of obtaining, using, and analyzing CCFDNA from blood will be discussed. View Full-Text
Keywords: circulating cell free DNA; neoplasms; early diagnosis; follow up on cancer treatment; prognosis circulating cell free DNA; neoplasms; early diagnosis; follow up on cancer treatment; prognosis
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Elshimali, Y.I.; Khaddour, H.; Sarkissyan, M.; Wu, Y.; Vadgama, J.V. The Clinical Utilization of Circulating Cell Free DNA (CCFDNA) in Blood of Cancer Patients. Int. J. Mol. Sci. 2013, 14, 18925-18958.

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