Int. J. Mol. Sci. 2013, 14(7), 13391-13402; doi:10.3390/ijms140713391
Article

Apoferritin Modified Magnetic Particles as Doxorubicin Carriers for Anticancer Drug Delivery

1email, 1email, 1email, 1,2email, 1email, 1,2email, 3email, 4email, 1,2email and 1,2,* email
Received: 19 April 2013; in revised form: 18 May 2013 / Accepted: 23 May 2013 / Published: 27 June 2013
(This article belongs to the Special Issue Magnetic Nanoparticles 2013)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Magnetic particle mediated transport in combination with nanomaterial based drug carrier has a great potential for targeted cancer therapy. In this study, doxorubicin encapsulation into the apoferritin and its conjugation with magnetic particles was investigated by capillary electrophoresis with laser-induced fluorescence detection (CE-LIF). The quantification of encapsulated doxorubicin was performed by fluorescence spectroscopy and compared to CE-LIF. Moreover, the significant enhancement of the doxorubicin signal was observed by addition of methanol into the sample solution.
Keywords: cancer; nanomedicine; magnetic particles; doxorubicin; nanoparticles
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MDPI and ACS Style

Blazkova, I.; Nguyen, H.V.; Dostalova, S.; Kopel, P.; Stanisavljevic, M.; Vaculovicova, M.; Stiborova, M.; Eckschlager, T.; Kizek, R.; Adam, V. Apoferritin Modified Magnetic Particles as Doxorubicin Carriers for Anticancer Drug Delivery. Int. J. Mol. Sci. 2013, 14, 13391-13402.

AMA Style

Blazkova I, Nguyen HV, Dostalova S, Kopel P, Stanisavljevic M, Vaculovicova M, Stiborova M, Eckschlager T, Kizek R, Adam V. Apoferritin Modified Magnetic Particles as Doxorubicin Carriers for Anticancer Drug Delivery. International Journal of Molecular Sciences. 2013; 14(7):13391-13402.

Chicago/Turabian Style

Blazkova, Iva; Nguyen, Hoai V.; Dostalova, Simona; Kopel, Pavel; Stanisavljevic, Maja; Vaculovicova, Marketa; Stiborova, Marie; Eckschlager, Tomas; Kizek, Rene; Adam, Vojtech. 2013. "Apoferritin Modified Magnetic Particles as Doxorubicin Carriers for Anticancer Drug Delivery." Int. J. Mol. Sci. 14, no. 7: 13391-13402.


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