Next Article in Journal
Towards the Identification of New Genes Involved in ABA-Dependent Abiotic Stresses Using Arabidopsis Suppressor Mutants of abh1 Hypersensitivity to ABA during Seed Germination
Next Article in Special Issue
Facile Synthesis of FeCo/Fe3O4 Nanocomposite with High Wave-Absorbing Properties
Previous Article in Journal
A Labile Pool of IQGAP1 Disassembles Endothelial Adherens Junctions
Previous Article in Special Issue
Preparation of Novel Poly(hydroxyethyl methacrylate-co-glycidyl methacrylate)-Grafted Core-Shell Magnetic Chitosan Microspheres and Immobilization of Lactase
Int. J. Mol. Sci. 2013, 14(7), 13391-13402; doi:10.3390/ijms140713391
Article

Apoferritin Modified Magnetic Particles as Doxorubicin Carriers for Anticancer Drug Delivery

1
, 1
, 1
, 1,2
, 1
, 1,2
, 3
, 4
, 1,2
 and 1,2,*
Received: 19 April 2013; in revised form: 18 May 2013 / Accepted: 23 May 2013 / Published: 27 June 2013
(This article belongs to the Special Issue Magnetic Nanoparticles 2013)
View Full-Text   |   Download PDF [1865 KB, uploaded 19 June 2014]   |   Browse Figures
Abstract: Magnetic particle mediated transport in combination with nanomaterial based drug carrier has a great potential for targeted cancer therapy. In this study, doxorubicin encapsulation into the apoferritin and its conjugation with magnetic particles was investigated by capillary electrophoresis with laser-induced fluorescence detection (CE-LIF). The quantification of encapsulated doxorubicin was performed by fluorescence spectroscopy and compared to CE-LIF. Moreover, the significant enhancement of the doxorubicin signal was observed by addition of methanol into the sample solution.
Keywords: cancer; nanomedicine; magnetic particles; doxorubicin; nanoparticles cancer; nanomedicine; magnetic particles; doxorubicin; nanoparticles
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |
EndNote


MDPI and ACS Style

Blazkova, I.; Nguyen, H.V.; Dostalova, S.; Kopel, P.; Stanisavljevic, M.; Vaculovicova, M.; Stiborova, M.; Eckschlager, T.; Kizek, R.; Adam, V. Apoferritin Modified Magnetic Particles as Doxorubicin Carriers for Anticancer Drug Delivery. Int. J. Mol. Sci. 2013, 14, 13391-13402.

AMA Style

Blazkova I, Nguyen HV, Dostalova S, Kopel P, Stanisavljevic M, Vaculovicova M, Stiborova M, Eckschlager T, Kizek R, Adam V. Apoferritin Modified Magnetic Particles as Doxorubicin Carriers for Anticancer Drug Delivery. International Journal of Molecular Sciences. 2013; 14(7):13391-13402.

Chicago/Turabian Style

Blazkova, Iva; Nguyen, Hoai V.; Dostalova, Simona; Kopel, Pavel; Stanisavljevic, Maja; Vaculovicova, Marketa; Stiborova, Marie; Eckschlager, Tomas; Kizek, Rene; Adam, Vojtech. 2013. "Apoferritin Modified Magnetic Particles as Doxorubicin Carriers for Anticancer Drug Delivery." Int. J. Mol. Sci. 14, no. 7: 13391-13402.


Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert