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Int. J. Mol. Sci. 2013, 14(5), 10307-10331; doi:10.3390/ijms140510307
Review

Methylated DNA and microRNA in Body Fluids as Biomarkers for Cancer Detection

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Received: 11 March 2013; in revised form: 1 April 2013 / Accepted: 25 April 2013 / Published: 16 May 2013
(This article belongs to the Special Issue Advances in Cancer Diagnosis)
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Abstract: Epigenetic alterations including DNA methylation and microRNAs (miRNAs) play important roles in the initiation and progression of human cancers. As the extensively studied epigenetic changes in tumors, DNA methylation and miRNAs are the most potential epigenetic biomarkers for cancer diagnosis. After the identification of circulating cell-free nuclear acids, increasing evidence demonstrated great potential of cell-free epigenetic biomarkers in the blood or other body fluids for cancer detection.
Keywords: cancer; biomarker; DNA methylation; miRNAs cancer; biomarker; DNA methylation; miRNAs
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Ma, Y.; Wang, X.; Jin, H. Methylated DNA and microRNA in Body Fluids as Biomarkers for Cancer Detection. Int. J. Mol. Sci. 2013, 14, 10307-10331.

AMA Style

Ma Y, Wang X, Jin H. Methylated DNA and microRNA in Body Fluids as Biomarkers for Cancer Detection. International Journal of Molecular Sciences. 2013; 14(5):10307-10331.

Chicago/Turabian Style

Ma, Yanning; Wang, Xian; Jin, Hongchuan. 2013. "Methylated DNA and microRNA in Body Fluids as Biomarkers for Cancer Detection." Int. J. Mol. Sci. 14, no. 5: 10307-10331.



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