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Development and Antibacterial Activity of Cashew Gum-Based Silver Nanoparticles
Biotec—Biodiversity and Biotechnology Research Center, Federal University of Piauí, Parnaíba, PI 64202020, Brazil
Medical Plants Research Center, Federal University of Piauí, Teresina, PI 64049550, Brazil
Federal Institute of Education, Science and Technology of Piauí, Parnaíba, PI 64210260, Brazil
Laboratory of Forensic Ridgeology, Institute of Civil Identification of Police, II/PCDF, 70610200 DF, Brazil
Laboratory of Cellular Immunology, School of Medicine, University of Brasília, Brasília, DF 70910900, Brazil
Laboratory of Parasitology, Butantan Institute, 05504900, São Paulo, SP, Brazil
Department of Veterinary Morphophysiology, Federal University of Piauí, Teresina, PI 64049550, Brazil
* Author to whom correspondence should be addressed.
Received: 26 November 2012; in revised form: 11 January 2013 / Accepted: 6 February 2013 / Published: 1 March 2013
Abstract: The present study describes the development of a green synthesis of silver nanoparticles reduced and stabilized by exuded gum from Anacardium occidentale L. and evaluates in vitro their antibacterial and cytotoxic activities. Characterization of cashew gum-based silver nanoparticles (AgNPs) was carried out based on UV–Vis spectroscopy, transmission electron microscopy and dynamic light scattering analysis which revealed that the synthesized silver nanoparticles were spherical in shape, measuring about 4 nm in size with a uniform dispersal. AgNPs presented antibacterial activity, especially against Gram-negative bacteria, in concentrations where no significant cytotoxicity was observed.
Keywords: silver nanoparticles; cashew gum; antibacterial activity; cytotoxicity
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Quelemes, P.V.; Araruna, F.B.; de Faria, B.E.F.; Kuckelhaus, S.A.S.; da Silva, D.A.; Mendonça, R.Z.; Eiras, C.; dos S. Soares, M.J.; Leite, J.R.S.A. Development and Antibacterial Activity of Cashew Gum-Based Silver Nanoparticles. Int. J. Mol. Sci. 2013, 14, 4969-4981.
Quelemes PV, Araruna FB, de Faria BEF, Kuckelhaus SAS, da Silva DA, Mendonça RZ, Eiras C, dos S. Soares MJ, Leite JRSA. Development and Antibacterial Activity of Cashew Gum-Based Silver Nanoparticles. International Journal of Molecular Sciences. 2013; 14(3):4969-4981.
Quelemes, Patrick V.; Araruna, Felipe B.; de Faria, Bruna E.F.; Kuckelhaus, Selma A.S.; da Silva, Durcilene A.; Mendonça, Ronaldo Z.; Eiras, Carla; dos S. Soares, Maria J.; Leite, José Roberto S.A. 2013. "Development and Antibacterial Activity of Cashew Gum-Based Silver Nanoparticles." Int. J. Mol. Sci. 14, no. 3: 4969-4981.