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Metabolomics as a Tool to Investigate Abiotic Stress Tolerance in Plants
Plant Ecophysiology and Biotechnology Laboratory, Departament of Agricultural and Environmental Sciences, Universitat Jaume I, Castello de la Plana E-12071, Spain
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Received: 31 December 2012; in revised form: 18 February 2013 / Accepted: 20 February 2013 / Published: 1 March 2013
Abstract: Metabolites reflect the integration of gene expression, protein interaction and other different regulatory processes and are therefore closer to the phenotype than mRNA transcripts or proteins alone. Amongst all –omics technologies, metabolomics is the most transversal and can be applied to different organisms with little or no modifications. It has been successfully applied to the study of molecular phenotypes of plants in response to abiotic stress in order to find particular patterns associated to stress tolerance. These studies have highlighted the essential involvement of primary metabolites: sugars, amino acids and Krebs cycle intermediates as direct markers of photosynthetic dysfunction as well as effectors of osmotic readjustment. On the contrary, secondary metabolites are more specific of genera and species and respond to particular stress conditions as antioxidants, Reactive Oxygen Species (ROS) scavengers, coenzymes, UV and excess radiation screen and also as regulatory molecules. In addition, the induction of secondary metabolites by several abiotic stress conditions could also be an effective mechanism of cross-protection against biotic threats, providing a link between abiotic and biotic stress responses. Moreover, the presence/absence and relative accumulation of certain metabolites along with gene expression data provides accurate markers (mQTL or MWAS) for tolerant crop selection in breeding programs.
Keywords: cold; heat; metabolite profiling; mQTL; omics; osmoprotectants; oxidative stress; salt stress; soil flooding; water stress
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Arbona, V.; Manzi, M.; Ollas, C.D.; Gómez-Cadenas, A. Metabolomics as a Tool to Investigate Abiotic Stress Tolerance in Plants. Int. J. Mol. Sci. 2013, 14, 4885-4911.
Arbona V, Manzi M, Ollas CD, Gómez-Cadenas A. Metabolomics as a Tool to Investigate Abiotic Stress Tolerance in Plants. International Journal of Molecular Sciences. 2013; 14(3):4885-4911.
Arbona, Vicent; Manzi, Matías; Ollas, Carlos D.; Gómez-Cadenas, Aurelio. 2013. "Metabolomics as a Tool to Investigate Abiotic Stress Tolerance in Plants." Int. J. Mol. Sci. 14, no. 3: 4885-4911.