Int. J. Mol. Sci. 2013, 14(3), 4670-4683; doi:10.3390/ijms14034670

Regulation of Translation Initiation under Biotic and Abiotic Stresses

1,†email, 1,†email, 1,†email, 1,†email, 2email and 1,* email
Received: 15 January 2013; in revised form: 20 February 2013 / Accepted: 20 February 2013 / Published: 26 February 2013
(This article belongs to the Special Issue Abiotic and Biotic Stress Tolerance Mechanisms in Plants)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Plants have developed versatile strategies to deal with the great variety of challenging conditions they are exposed to. Among them, the regulation of translation is a common target to finely modulate gene expression both under biotic and abiotic stress situations. Upon environmental challenges, translation is regulated to reduce the consumption of energy and to selectively synthesize proteins involved in the proper establishment of the tolerance response. In the case of viral infections, the situation is more complex, as viruses have evolved unconventional mechanisms to regulate translation in order to ensure the production of the viral encoded proteins using the plant machinery. Although the final purpose is different, in some cases, both plants and viruses share common mechanisms to modulate translation. In others, the mechanisms leading to the control of translation are viral- or stress-specific. In this paper, we review the different mechanisms involved in the regulation of translation initiation under virus infection and under environmental stress in plants. In addition, we describe the main features within the viral RNAs and the cellular mRNAs that promote their selective translation in plants undergoing biotic and abiotic stress situations.
Keywords: regulation of translation; eIF4E; eIF2α; plant abiotic stress; IRES; cIRES; CITES; cap-dependent enhancers
PDF Full-text Download PDF Full-Text [194 KB, uploaded 19 June 2014 04:44 CEST]

Export to BibTeX |

MDPI and ACS Style

Echevarría-Zomeño, S.; Yángüez, E.; Fernández-Bautista, N.; Castro-Sanz, A.B.; Ferrando, A.; Castellano, M.M. Regulation of Translation Initiation under Biotic and Abiotic Stresses. Int. J. Mol. Sci. 2013, 14, 4670-4683.

AMA Style

Echevarría-Zomeño S, Yángüez E, Fernández-Bautista N, Castro-Sanz AB, Ferrando A, Castellano MM. Regulation of Translation Initiation under Biotic and Abiotic Stresses. International Journal of Molecular Sciences. 2013; 14(3):4670-4683.

Chicago/Turabian Style

Echevarría-Zomeño, Sira; Yángüez, Emilio; Fernández-Bautista, Nuria; Castro-Sanz, Ana B.; Ferrando, Alejandro; Castellano, M. M. 2013. "Regulation of Translation Initiation under Biotic and Abiotic Stresses." Int. J. Mol. Sci. 14, no. 3: 4670-4683.

Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert