Abstract: To date, few reports focused primarily on detecting colorectal laterally spreading tumors (LSTs) have been published. The aim of this study was to determine the visibility of LSTs on computed tomographic colonography (CTC) compared with that on colonoscopy as a standard. We retrospectively reviewed and matched data on endoscopic and CTC reports in 157 patients (161 LSTs) who received a multidetector CT scan using contrast media immediately after total colonoscopy at the National Cancer Center Hospital in Tokyo, Japan, between December 2005 and August 2010. The results of the total colonoscopy were known at the time of the CTC procedure and reading. Of the 161 LSTs detected on colonoscopy, 138 were observed and matched by CTC (86%). Of the 91 granular type LSTs (LST-Gs), 88 (97%) were observed and matched, while of the 70 non-granular type LSTs (LST-NGs), 50 (71%) were observed and matched by CTC (p < 0.0001). CTC enabled observation of 73% (22/30) of 20–29 mm, 83% (35/42) of 30–39 mm, 88% (49/56) of 40–59 mm, and 97% (32/33) of ≥60 mm tumors. The rate of observed LSTs by CTC was 86% (97% of LST-G, 71% of LST-NG) of the LSTs found during total colonoscopy.
Keywords: colonoscopy; colorectal cancer; computed tomographic colonography; laterally spreading tumor (LST
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Kakugawa, Y.; Saito, Y.; Matsuda, T.; Nakajima, T.; Miyake, M.; Iinuma, G. Colorectal Laterally Spreading Tumors by Computed Tomographic Colonography. Int. J. Mol. Sci. 2013, 14, 23629-23638.
Kakugawa Y, Saito Y, Matsuda T, Nakajima T, Miyake M, Iinuma G. Colorectal Laterally Spreading Tumors by Computed Tomographic Colonography. International Journal of Molecular Sciences. 2013; 14(12):23629-23638.
Kakugawa, Yasuo; Saito, Yutaka; Matsuda, Takahisa; Nakajima, Takeshi; Miyake, Mototaka; Iinuma, Gen. 2013. "Colorectal Laterally Spreading Tumors by Computed Tomographic Colonography." Int. J. Mol. Sci. 14, no. 12: 23629-23638.