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Modeling Human Liver Biology Using Stem Cell-Derived Hepatocytes
Shantou University Medical College, Shantou 515041, China
MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh EH16 4UU, UK
MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow G11 5JR, UK
* Author to whom correspondence should be addressed.
Received: 28 September 2013; in revised form: 28 October 2013 / Accepted: 30 October 2013 / Published: 6 November 2013
Abstract: Stem cell-derived hepatocytes represent promising models to study human liver biology and disease. This concise review discusses the recent progresses in the field, with a focus on human liver disease, drug metabolism and virus infection.
Keywords: drug metabolism; liver disease; stem cell; stem cell-derived hepatocytes; cell based models
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Cite This Article
MDPI and ACS Style
Sun, P.; Zhou, X.; Farnworth, S.L.; Patel, A.H.; Hay, D.C. Modeling Human Liver Biology Using Stem Cell-Derived Hepatocytes. Int. J. Mol. Sci. 2013, 14, 22011-22021.
Sun P, Zhou X, Farnworth SL, Patel AH, Hay DC. Modeling Human Liver Biology Using Stem Cell-Derived Hepatocytes. International Journal of Molecular Sciences. 2013; 14(11):22011-22021.
Sun, Pingnan; Zhou, Xiaoling; Farnworth, Sarah L.; Patel, Arvind H.; Hay, David C. 2013. "Modeling Human Liver Biology Using Stem Cell-Derived Hepatocytes." Int. J. Mol. Sci. 14, no. 11: 22011-22021.