Int. J. Mol. Sci. 2012, 13(6), 7260-7270; doi:10.3390/ijms13067260

Evaluation of the Antioxidant Capacity of Synthesized Coumarins

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Received: 14 May 2012; in revised form: 25 May 2012 / Accepted: 28 May 2012 / Published: 13 June 2012
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Coumarins are secondary metabolites that are widely distributed within the plant kingdom, some of which have been extensively studied for their antioxidant properties. The antioxidant activity of coumarins assayed in the present study was measured by different methods, namely the 1,1-diphenyl-2-picryl-hydrazyl (DPPH) method, cyclic voltammetry and the antioxidant capacity against peroxyl radicals (ACAP) method. The 7,8-dihydroxy-4-methylcoumarin (LaSOM 78), 5-carboxy-7,8-dihydroxy-4-methylcoumarin (LaSOM 79), and 6,7-dihydroxycoumarin (Esculetin) compounds proved to be the most active, showing the highest capacity to deplete the DPPH radicals, the highest antioxidant capacity against peroxyl radicals, and the lowest values of potential oxidation.
Keywords: antioxidant capacity; peroxyl radicals; coumarins; DPPH; cyclic voltammetry
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MDPI and ACS Style

Vianna, D.R.; Bubols, G.; Meirelles, G.; Silva, B.V.; da Rocha, A.; Lanznaster, M.; Monserrat, J.M.; Garcia, S.C.; von Poser, G.; Eifler-Lima, V.L. Evaluation of the Antioxidant Capacity of Synthesized Coumarins. Int. J. Mol. Sci. 2012, 13, 7260-7270.

AMA Style

Vianna DR, Bubols G, Meirelles G, Silva BV, da Rocha A, Lanznaster M, Monserrat JM, Garcia SC, von Poser G, Eifler-Lima VL. Evaluation of the Antioxidant Capacity of Synthesized Coumarins. International Journal of Molecular Sciences. 2012; 13(6):7260-7270.

Chicago/Turabian Style

Vianna, Damiana R.; Bubols, Guilherme; Meirelles, Gabriela; Silva, Bárbara V.; da Rocha, Alessandra; Lanznaster, Maurício; Monserrat, José Maria; Garcia, Solange Cristina; von Poser, Gilsane; Eifler-Lima, Vera Lucia. 2012. "Evaluation of the Antioxidant Capacity of Synthesized Coumarins." Int. J. Mol. Sci. 13, no. 6: 7260-7270.

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