Evaluation of the Antioxidant Capacity of Synthesized Coumarins
AbstractCoumarins are secondary metabolites that are widely distributed within the plant kingdom, some of which have been extensively studied for their antioxidant properties. The antioxidant activity of coumarins assayed in the present study was measured by different methods, namely the 1,1-diphenyl-2-picryl-hydrazyl (DPPH•) method, cyclic voltammetry and the antioxidant capacity against peroxyl radicals (ACAP) method. The 7,8-dihydroxy-4-methylcoumarin (LaSOM 78), 5-carboxy-7,8-dihydroxy-4-methylcoumarin (LaSOM 79), and 6,7-dihydroxycoumarin (Esculetin) compounds proved to be the most active, showing the highest capacity to deplete the DPPH radicals, the highest antioxidant capacity against peroxyl radicals, and the lowest values of potential oxidation.
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Vianna, D.R.; Bubols, G.; Meirelles, G.; Silva, B.V.; da Rocha, A.; Lanznaster, M.; Monserrat, J.M.; Garcia, S.C.; von Poser, G.; Eifler-Lima, V.L. Evaluation of the Antioxidant Capacity of Synthesized Coumarins. Int. J. Mol. Sci. 2012, 13, 7260-7270.
Vianna DR, Bubols G, Meirelles G, Silva BV, da Rocha A, Lanznaster M, Monserrat JM, Garcia SC, von Poser G, Eifler-Lima VL. Evaluation of the Antioxidant Capacity of Synthesized Coumarins. International Journal of Molecular Sciences. 2012; 13(6):7260-7270.Chicago/Turabian Style
Vianna, Damiana R.; Bubols, Guilherme; Meirelles, Gabriela; Silva, Bárbara V.; da Rocha, Alessandra; Lanznaster, Maurício; Monserrat, José Maria; Garcia, Solange Cristina; von Poser, Gilsane; Eifler-Lima, Vera Lucia. 2012. "Evaluation of the Antioxidant Capacity of Synthesized Coumarins." Int. J. Mol. Sci. 13, no. 6: 7260-7270.