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Int. J. Mol. Sci. 2012, 13(4), 5242-5253; doi:10.3390/ijms13045242

Sol-Gel-Derived Hydroxyapatite-Carbon Nanotube/Titania Coatings on Titanium Substrates

1 Department of Prosthodontics, School and Hospital of Stomatology, Wenzhou Medical College, Wenzhou 325027, China 2 State Key Laboratory of Oral Diseases, West China Stomatology Hospital, Sichuan University, Chengdu 610041, China These authors contributed equally to this work.
* Author to whom correspondence should be addressed.
Received: 29 February 2012 / Revised: 9 March 2012 / Accepted: 18 April 2012 / Published: 24 April 2012
(This article belongs to the Section Material Sciences and Nanotechnology)
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In this paper, hydroxyapatite-carbon nanotube/titania (HA-CNT/TiO2) double layer coatings were successfully developed on titanium (Ti) substrates intended for biomedical applications. A TiO2 coating was firstly developed by anodization to improve bonding between HA and Ti, and then the layer of HA and CNTs was coated on the surface by the sol-gel process to improve the biocompatibility and mechanical properties of Ti. The surfaces of double layer coatings were uniform and crack-free with a thickness of about 7 μm. The bonding strength of the HA-CNT/TiO2 coating was higher than that of the pure HA and HA-CNT coatings. Additionally, in vitro cell experiments showed that CNTs promoted the adhesion of preosteoblasts on the HA-CNT/TiO2 double layer coatings. These unique surfaces combined with the osteoconductive properties of HA exhibited the excellent mechanical properties of CNTs. Therefore, the developed HA-CNT/TiO2 coatings on Ti substrates might be a promising material for bone replacement.
Keywords: hydroxyapatite; carbon nanotubes; titania; anodization; sol-gel process hydroxyapatite; carbon nanotubes; titania; anodization; sol-gel process
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Ji, X.; Lou, W.; Wang, Q.; Ma, J.; Xu, H.; Bai, Q.; Liu, C.; Liu, J. Sol-Gel-Derived Hydroxyapatite-Carbon Nanotube/Titania Coatings on Titanium Substrates. Int. J. Mol. Sci. 2012, 13, 5242-5253.

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