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Sol-Gel-Derived Hydroxyapatite-Carbon Nanotube/Titania Coatings on Titanium Substrates
Department of Prosthodontics, School and Hospital of Stomatology, Wenzhou Medical College, Wenzhou 325027, China
State Key Laboratory of Oral Diseases, West China Stomatology Hospital, Sichuan University, Chengdu 610041, China
These authors contributed equally to this work.
* Author to whom correspondence should be addressed.
Received: 29 February 2012; in revised form: 9 March 2012 / Accepted: 18 April 2012 / Published: 24 April 2012
Abstract: In this paper, hydroxyapatite-carbon nanotube/titania (HA-CNT/TiO2) double layer coatings were successfully developed on titanium (Ti) substrates intended for biomedical applications. A TiO2 coating was firstly developed by anodization to improve bonding between HA and Ti, and then the layer of HA and CNTs was coated on the surface by the sol-gel process to improve the biocompatibility and mechanical properties of Ti. The surfaces of double layer coatings were uniform and crack-free with a thickness of about 7 μm. The bonding strength of the HA-CNT/TiO2 coating was higher than that of the pure HA and HA-CNT coatings. Additionally, in vitro cell experiments showed that CNTs promoted the adhesion of preosteoblasts on the HA-CNT/TiO2 double layer coatings. These unique surfaces combined with the osteoconductive properties of HA exhibited the excellent mechanical properties of CNTs. Therefore, the developed HA-CNT/TiO2 coatings on Ti substrates might be a promising material for bone replacement.
Keywords: hydroxyapatite; carbon nanotubes; titania; anodization; sol-gel process
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MDPI and ACS Style
Ji, X.; Lou, W.; Wang, Q.; Ma, J.; Xu, H.; Bai, Q.; Liu, C.; Liu, J. Sol-Gel-Derived Hydroxyapatite-Carbon Nanotube/Titania Coatings on Titanium Substrates. Int. J. Mol. Sci. 2012, 13, 5242-5253.
Ji X, Lou W, Wang Q, Ma J, Xu H, Bai Q, Liu C, Liu J. Sol-Gel-Derived Hydroxyapatite-Carbon Nanotube/Titania Coatings on Titanium Substrates. International Journal of Molecular Sciences. 2012; 13(4):5242-5253.
Ji, Xiaoli; Lou, Weiwei; Wang, Qi; Ma, Jianfeng; Xu, Haihong; Bai, Qing; Liu, Chuantong; Liu, Jinsong. 2012. "Sol-Gel-Derived Hydroxyapatite-Carbon Nanotube/Titania Coatings on Titanium Substrates." Int. J. Mol. Sci. 13, no. 4: 5242-5253.