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Int. J. Mol. Sci. 2012, 13(3), 3414-3430; doi:10.3390/ijms13033414
Review

Computational Analysis of Axonal Transport: A Novel Assessment of Neurotoxicity, Neuronal Development and Functions

1,* , 1
 and 2,*
Received: 11 January 2012; in revised form: 25 January 2012 / Accepted: 23 February 2012 / Published: 12 March 2012
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Abstract: Axonal transport plays a crucial role in neuronal morphogenesis, survival and function. Despite its importance, however, the molecular mechanisms of axonal transport remain mostly unknown because a simple and quantitative assay system for monitoring this cellular process has been lacking. In order to better characterize the mechanisms involved in axonal transport, we formulate a novel computer-assisted monitoring system of axonal transport. Potential uses of this system and implications for future studies will be discussed.
Keywords: axonal transport; anti-neoplastic agents; microtubules; kinesin; dynein axonal transport; anti-neoplastic agents; microtubules; kinesin; dynein
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Goshima, Y.; Hida, T.; Gotoh, T. Computational Analysis of Axonal Transport: A Novel Assessment of Neurotoxicity, Neuronal Development and Functions. Int. J. Mol. Sci. 2012, 13, 3414-3430.

AMA Style

Goshima Y, Hida T, Gotoh T. Computational Analysis of Axonal Transport: A Novel Assessment of Neurotoxicity, Neuronal Development and Functions. International Journal of Molecular Sciences. 2012; 13(3):3414-3430.

Chicago/Turabian Style

Goshima, Yoshio; Hida, Tomonobu; Gotoh, Toshiyuki. 2012. "Computational Analysis of Axonal Transport: A Novel Assessment of Neurotoxicity, Neuronal Development and Functions." Int. J. Mol. Sci. 13, no. 3: 3414-3430.



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