New Triterpenoids with Cytotoxic Activity from Actinidia Valvata

doi:10.3390/ijms131114865

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Int. J. Mol. Sci. 2012, 13(11), 14865-14870; doi:10.3390/ijms131114865

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New Triterpenoids with Cytotoxic Activity from Actinidia Valvata

Li-Ping Qu^†, Guo-Yin Zheng^†, Yong-Hua Su, Hui-Qing Zhang, Yan-Long Yang, Hai-Liang Xin and Chang-Quan Ling*

Department of Traditional Chinese Medicine, Changhai Hospital of Second Military Medical University, Shanghai 200433, China ^† These authors contributed equally to this work.

* Author to whom correspondence should be addressed.

Received: 17 September 2012; in revised form: 19 October 2012 / Accepted: 22 October 2012 / Published: 13 November 2012

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Abstract: Two new triterpenoids, 30-O-β-D-glucopyranosyloxy-2α,3α,24-trihydroxyurs-12, 18-diene-28-oic acid O-β-D-glucopyranosyl ester (1) and 2α,3β,3,30-tetrahydroxyurs-12, 18-diene-28-oic acid O-β-D-glucopyranosyl ester (2) were isolated from roots of Actinidia valvata Dunn. Their structures were elucidated by means of extensive spectroscopic studies. Both these two new compounds showed moderate cytotoxic activity in vitro against BEL-7402 and SMMC-7721 tumor cell line.

Keywords: Actinidia valvata Dunn; triterpenoid; cytotoxic activity

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MDPI and ACS Style

Qu, L.-P.; Zheng, G.-Y.; Su, Y.-H.; Zhang, H.-Q.; Yang, Y.-L.; Xin, H.-L.; Ling, C.-Q. New Triterpenoids with Cytotoxic Activity from Actinidia Valvata. Int. J. Mol. Sci. 2012, 13, 14865-14870.

AMA Style

Qu L-P, Zheng G-Y, Su Y-H, Zhang H-Q, Yang Y-L, Xin H-L, Ling C-Q. New Triterpenoids with Cytotoxic Activity from Actinidia Valvata. International Journal of Molecular Sciences. 2012; 13(11):14865-14870.

Chicago/Turabian Style

Qu, Li-Ping; Zheng, Guo-Yin; Su, Yong-Hua; Zhang, Hui-Qing; Yang, Yan-Long; Xin, Hai-Liang; Ling, Chang-Quan. 2012. "New Triterpenoids with Cytotoxic Activity from Actinidia Valvata." Int. J. Mol. Sci. 13, no. 11: 14865-14870.

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