Next Article in Journal
Acidic Pretreatment of Wheat Straw in Decanol for the Production of Surfactant, Lignin and Glucose
Previous Article in Journal
Human Gene Control by Vital Oncogenes: Revisiting a Theoretical Model and Its Implications for Targeted Cancer Therapy
Article Menu

Export Article

Open AccessArticle
Int. J. Mol. Sci. 2012, 13(1), 336-347; doi:10.3390/ijms13010336

Wound Healing Activity of Elaeis guineensis Leaf Extract Ointment

1
Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, 11800 USM, Pulau Pinang, Malaysia
2
Department of Biotechnology, Faculty of Applied Sciences, Asian Institute of Medicine, Science and Technology, 08000 Sungai Petani, Kedah, Malaysia
*
Author to whom correspondence should be addressed.
Received: 21 July 2011 / Revised: 2 November 2011 / Accepted: 28 November 2011 / Published: 28 December 2011
(This article belongs to the Section Biochemistry, Molecular Biology and Biophysics)
View Full-Text   |   Download PDF [1102 KB, 19 June 2014; original version 19 June 2014]   |  

Abstract

Elaeis guineensis of the Arecaceae family is widely used in the traditional medicine of societies in West Africa for treating various ailments. To validate the ethnotherapeutic claims of the plant in skin diseases, wound healing activity was studied. The results showed that E. guineensis leaf extract had potent wound healing capacity as evident from the better wound closure (P < 0.05), improved tissue regeneration at the wound site, and supporting histopathological parameters pertaining to wound healing. Matrix metalloproteinases expression correlated well with the results thus confirming efficacy of E. guineensis in the treatment of the wound. E. guineensis accelerated wound healing in rats, thus supporting its traditional use. The result of this study suggested that, used efficiently, oil palm leaf extract is a renewable resource with wound healing properties.
Keywords: Elaeis guineensis; wound healing activity; matrix metalloproteinases; gelatin zymography Elaeis guineensis; wound healing activity; matrix metalloproteinases; gelatin zymography
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Sasidharan, S.; Logeswaran, S.; Latha, L.Y. Wound Healing Activity of Elaeis guineensis Leaf Extract Ointment. Int. J. Mol. Sci. 2012, 13, 336-347.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top