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Int. J. Mol. Sci. 2012, 13(1), 173-179; doi:10.3390/ijms13010173
Review

Significance of Dietary Antioxidants for Health

Received: 17 November 2011 / Revised: 2 December 2011 / Accepted: 8 December 2011 / Published: 23 December 2011
(This article belongs to the Section Bioactives and Nutraceuticals)
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Abstract

Since evidence became available that free radicals were involved in mechanisms for the development of major diseases, including cardiovascular disease and cancer, there has been considerable research into the properties of natural dietary antioxidants. However, it has become clear that dietary antioxidants can only have beneficial effects in vivo by radical scavenging or effects on redox potential if they are present in tissues or bodily fluids at sufficient concentrations. For many dietary components, absorption is limited or metabolism into derivatives reduces the antioxidant capacity. For many dietary phytochemicals, direct antioxidant effects may be less important for health than other effects including effects on cell signalling or gene expression in vivo.
Keywords: antioxidants; bioavailability; health antioxidants; bioavailability; health
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Gordon, M.H. Significance of Dietary Antioxidants for Health. Int. J. Mol. Sci. 2012, 13, 173-179.

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