Int. J. Mol. Sci. 2012, 13(1), 1126-1153; doi:10.3390/ijms13011126
Review

Clinical Significance of Serum Biomarkers in Pediatric Solid Mediastinal and Abdominal Tumors

John A. Sandoval 1,* email, Linda H. Malkas 2 email and Robert J. Hickey 2 email
1 Department of Surgery, St. Jude Children’s Research Hospital, 262 Danny Thomas Place, MS332, Room D3040G, Memphis, TN 38105, USA 2 City of Hope Cancer Center, Duarte, CA 91010, USA
* Author to whom correspondence should be addressed.
Received: 7 December 2011; in revised form: 1 January 2012 / Accepted: 16 January 2012 / Published: 20 January 2012
(This article belongs to the Section Molecular Diagnostics)
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Abstract: Childhood cancer is the leading cause of death by disease among U.S. children between infancy and age 15. Despite successes in treating solid tumors such as Wilms tumor, disappointments in the outcomes of high-risk solid tumors like neuroblastoma have precipitated efforts towards the early and accurate detection of these malignancies. This review summarizes available solid tumor serum biomarkers with a special focus on mediastinal and abdominal cancers in children.
Keywords: pediatric solid tumors; mediastinal mass; abdominal mass; serum biomarkers

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MDPI and ACS Style

Sandoval, J.A.; Malkas, L.H.; Hickey, R.J. Clinical Significance of Serum Biomarkers in Pediatric Solid Mediastinal and Abdominal Tumors. Int. J. Mol. Sci. 2012, 13, 1126-1153.

AMA Style

Sandoval JA, Malkas LH, Hickey RJ. Clinical Significance of Serum Biomarkers in Pediatric Solid Mediastinal and Abdominal Tumors. International Journal of Molecular Sciences. 2012; 13(1):1126-1153.

Chicago/Turabian Style

Sandoval, John A.; Malkas, Linda H.; Hickey, Robert J. 2012. "Clinical Significance of Serum Biomarkers in Pediatric Solid Mediastinal and Abdominal Tumors." Int. J. Mol. Sci. 13, no. 1: 1126-1153.

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