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Int. J. Mol. Sci. 2012, 13(1), 1029-1038; doi:10.3390/ijms13011029
Article

Structural Elucidation and Bioactivity of Biflavonoids from the Stems of Wikstroemia taiwanensis

1,* , 2
 and
3
1 Department of Pharmacy, Chia-Nan University of Pharmacy and Science, Tainan 71710, Taiwan 2 School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 80708, Taiwan 3 Department of Medical Laboratory Science and Biotechnology, College of Health Sciences, Kaohsiung Medical University, Kaohsiung 80708, Taiwan
* Author to whom correspondence should be addressed.
Received: 6 December 2011 / Revised: 1 January 2012 / Accepted: 10 January 2012 / Published: 18 January 2012
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Abstract

Three new biflavonoids, wikstaiwanones A–C (13), along with four known compounds (47) were isolated from the stems of Wikstroemia taiwanensis (Thymelaeaceae). Their structures were elucidated by spectroscopic analysis. Compounds 4 and 5 showed antitubercular activity against Mycobacterium tuberculosis with MIC values of 15 μg/mL, respectively.
Keywords: Wikstroemia taiwanensis; Thymelaeaceae; stem; biflavonoid; antitubercular activity Wikstroemia taiwanensis; Thymelaeaceae; stem; biflavonoid; antitubercular activity
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Chen, L.-Y.; Chen, I.-S.; Peng, C.-F. Structural Elucidation and Bioactivity of Biflavonoids from the Stems of Wikstroemia taiwanensis. Int. J. Mol. Sci. 2012, 13, 1029-1038.

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