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Int. J. Mol. Sci. 2012, 13(1), 1029-1038; doi:10.3390/ijms13011029
Article

Structural Elucidation and Bioactivity of Biflavonoids from the Stems of Wikstroemia taiwanensis

1,* , 2
 and 3
1 Department of Pharmacy, Chia-Nan University of Pharmacy and Science, Tainan 71710, Taiwan 2 School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 80708, Taiwan 3 Department of Medical Laboratory Science and Biotechnology, College of Health Sciences, Kaohsiung Medical University, Kaohsiung 80708, Taiwan
* Author to whom correspondence should be addressed.
Received: 6 December 2011 / Revised: 1 January 2012 / Accepted: 10 January 2012 / Published: 18 January 2012
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Abstract

Three new biflavonoids, wikstaiwanones A–C (13), along with four known compounds (47) were isolated from the stems of Wikstroemia taiwanensis (Thymelaeaceae). Their structures were elucidated by spectroscopic analysis. Compounds 4 and 5 showed antitubercular activity against Mycobacterium tuberculosis with MIC values of 15 μg/mL, respectively.
Keywords: Wikstroemia taiwanensis; Thymelaeaceae; stem; biflavonoid; antitubercular activity Wikstroemia taiwanensis; Thymelaeaceae; stem; biflavonoid; antitubercular activity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Chen, L.-Y.; Chen, I.-S.; Peng, C.-F. Structural Elucidation and Bioactivity of Biflavonoids from the Stems of Wikstroemia taiwanensis. Int. J. Mol. Sci. 2012, 13, 1029-1038.

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Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert