Next Article in Journal
Next Article in Special Issue
Previous Article in Journal
Previous Article in Special Issue
Int. J. Mol. Sci. 2011, 12(9), 5782-5796; doi:10.3390/ijms12095782
Article

A Sweet Killer: Mesoporous Polysaccharide Confined Silver Nanoparticles for Antibacterial Applications

1,†,* , 1
, 2
 and 1
Received: 12 August 2011; Accepted: 23 August 2011 / Published: 9 September 2011
(This article belongs to the Special Issue Advances in Green Chemistry and Sustainable Chemistry 2011)
View Full-Text   |   Download PDF [759 KB, updated 19 June 2014; original version uploaded 19 June 2014]   |   Browse Figures
Abstract: Silver nanoparticles (AgNP) confined within porous starch have been prepared in a simple, green and efficient manner, utilising the nanoporous structure of predominantly mesoporous starch (MS) to act as nanoparticle stabiliser, support and reducing surface. MS/AgNP materials present high surface areas (SBET > 150 m2 g−1) and mesopore volumes (Vmeso > 0.45 cm3 g−1). The interaction of the AgNP precursor and forming nanoparticle nuclei with the mesoporous domains of the porous polysaccharide, direct porosity to increasingly narrower and more defined pore size distributions, indicative of a degree of cooperative assembly. Transmission electron microscopy images indicated the presence of spherical AgNP of a size reflective of the porous polysaccharide mesopore diameter (e.g., 5–25 nm), whilst XPS analysis confirmed the metallic Ag0 state. Materials were prepared at relatively low Ag loadings (< 0.18 mmol g−1), demonstrating excellent antimicrobial activity in solid and liquid phase testing against Gram negative (E. coli) and positive (S. aureus) model bacteria. The resulting materials are biocompatible and present a useful solid porous carbohydrate-based polymer vehicle to control the AgNP size regime and facilitate transference to a biological environment.
Keywords: antibacterial; mesoporous; nanoparticles; nanotechnology; polysaccharide; silver; starch antibacterial; mesoporous; nanoparticles; nanotechnology; polysaccharide; silver; starch
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |
EndNote


MDPI and ACS Style

White, R.J.; Budarin, V.L.; Moir, J.W.; Clark, J.H. A Sweet Killer: Mesoporous Polysaccharide Confined Silver Nanoparticles for Antibacterial Applications. Int. J. Mol. Sci. 2011, 12, 5782-5796.

AMA Style

White RJ, Budarin VL, Moir JW, Clark JH. A Sweet Killer: Mesoporous Polysaccharide Confined Silver Nanoparticles for Antibacterial Applications. International Journal of Molecular Sciences. 2011; 12(9):5782-5796.

Chicago/Turabian Style

White, Robin J.; Budarin, Vitaly L.; Moir, James W.B.; Clark, James H. 2011. "A Sweet Killer: Mesoporous Polysaccharide Confined Silver Nanoparticles for Antibacterial Applications." Int. J. Mol. Sci. 12, no. 9: 5782-5796.



Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert