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Int. J. Mol. Sci. 2011, 12(6), 3888-3927; doi:10.3390/ijms12063888

Inorganic-Organic Hybrid Nanomaterials for Therapeutic and Diagnostic Imaging Applications

1,†,*  and 2,†
1 Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA 2 Department of Bioenvironmental Engineering, Chung Yuan Christian University, Chung Li, 2023, Taiwan These authors contributed equally to this work.
* Author to whom correspondence should be addressed.
Received: 11 April 2011 / Accepted: 31 May 2011 / Published: 10 June 2011
(This article belongs to the Special Issue Bioactive Nanoparticles (special issue))
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Nanotechnology offers outstanding potential for future biomedical applications. In particular, due to their unique characteristics, hybrid nanomaterials have recently been investigated as promising platforms for imaging and therapeutic applications. This class of nanoparticles can not only retain valuable features of both inorganic and organic moieties, but also provides the ability to systematically modify the properties of the hybrid material through the combination of functional elements. Moreover, the conjugation of targeting moieties on the surface of these nanomaterials gives them specific targeted imaging and therapeutic properties. In this review, we summarize the recent reports in the synthesis of hybrid nanomaterials and their applications in biomedical areas. Their applications as imaging and therapeutic agents in vivo will be highlighted.
Keywords: hybrid nanoparticles; therapeutic and diagnostic imaging applications; nanomedicine hybrid nanoparticles; therapeutic and diagnostic imaging applications; nanomedicine
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Vivero-Escoto, J.L.; Huang, Y.-T. Inorganic-Organic Hybrid Nanomaterials for Therapeutic and Diagnostic Imaging Applications. Int. J. Mol. Sci. 2011, 12, 3888-3927.

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