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Micro Electromechanical Systems (MEMS) Based Microfluidic Devices for Biomedical Applications
School of Engineering and Technology, Asian Institute of Technology (AIT), Bangkok 12120, Thailand
* Author to whom correspondence should be addressed.
Received: 10 April 2011; in revised form: 3 May 2011 / Accepted: 19 May 2011 / Published: 7 June 2011
Abstract: Micro Electromechanical Systems (MEMS) based microfluidic devices have gained popularity in biomedicine field over the last few years. In this paper, a comprehensive overview of microfluidic devices such as micropumps and microneedles has been presented for biomedical applications. The aim of this paper is to present the major features and issues related to micropumps and microneedles, e.g., working principles, actuation methods, fabrication techniques, construction, performance parameters, failure analysis, testing, safety issues, applications, commercialization issues and future prospects. Based on the actuation mechanisms, the micropumps are classified into two main types, i.e., mechanical and non-mechanical micropumps. Microneedles can be categorized according to their structure, fabrication process, material, overall shape, tip shape, size, array density and application. The presented literature review on micropumps and microneedles will provide comprehensive information for researchers working on design and development of microfluidic devices for biomedical applications.
Keywords: drug delivery system; microfluidics; micropumps; microneedles
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Ashraf, M.W.; Tayyaba, S.; Afzulpurkar, N. Micro Electromechanical Systems (MEMS) Based Microfluidic Devices for Biomedical Applications. Int. J. Mol. Sci. 2011, 12, 3648-3704.
Ashraf MW, Tayyaba S, Afzulpurkar N. Micro Electromechanical Systems (MEMS) Based Microfluidic Devices for Biomedical Applications. International Journal of Molecular Sciences. 2011; 12(6):3648-3704.
Ashraf, Muhammad Waseem; Tayyaba, Shahzadi; Afzulpurkar, Nitin. 2011. "Micro Electromechanical Systems (MEMS) Based Microfluidic Devices for Biomedical Applications." Int. J. Mol. Sci. 12, no. 6: 3648-3704.