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Int. J. Mol. Sci. 2011, 12(6), 3648-3704; doi:10.3390/ijms12063648
Review

Micro Electromechanical Systems (MEMS) Based Microfluidic Devices for Biomedical Applications

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Received: 10 April 2011; in revised form: 3 May 2011 / Accepted: 19 May 2011 / Published: 7 June 2011
(This article belongs to the Special Issue Microfluidics)
Abstract: Micro Electromechanical Systems (MEMS) based microfluidic devices have gained popularity in biomedicine field over the last few years. In this paper, a comprehensive overview of microfluidic devices such as micropumps and microneedles has been presented for biomedical applications. The aim of this paper is to present the major features and issues related to micropumps and microneedles, e.g., working principles, actuation methods, fabrication techniques, construction, performance parameters, failure analysis, testing, safety issues, applications, commercialization issues and future prospects. Based on the actuation mechanisms, the micropumps are classified into two main types, i.e., mechanical and non-mechanical micropumps. Microneedles can be categorized according to their structure, fabrication process, material, overall shape, tip shape, size, array density and application. The presented literature review on micropumps and microneedles will provide comprehensive information for researchers working on design and development of microfluidic devices for biomedical applications.
Keywords: drug delivery system; microfluidics; micropumps; microneedles drug delivery system; microfluidics; micropumps; microneedles
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Ashraf, M.W.; Tayyaba, S.; Afzulpurkar, N. Micro Electromechanical Systems (MEMS) Based Microfluidic Devices for Biomedical Applications. Int. J. Mol. Sci. 2011, 12, 3648-3704.

AMA Style

Ashraf MW, Tayyaba S, Afzulpurkar N. Micro Electromechanical Systems (MEMS) Based Microfluidic Devices for Biomedical Applications. International Journal of Molecular Sciences. 2011; 12(6):3648-3704.

Chicago/Turabian Style

Ashraf, Muhammad Waseem; Tayyaba, Shahzadi; Afzulpurkar, Nitin. 2011. "Micro Electromechanical Systems (MEMS) Based Microfluidic Devices for Biomedical Applications." Int. J. Mol. Sci. 12, no. 6: 3648-3704.


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