Int. J. Mol. Sci. 2010, 11(9), 3209-3225; doi:10.3390/ijms11093209
Review

Biomarkers for Colorectal Cancer

1,2,* email, 3, 4email and 5email
Received: 18 August 2010; in revised form: 2 September 2010 / Accepted: 3 September 2010 / Published: 13 September 2010
(This article belongs to the Special Issue Biomarkers)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Colorectal cancer (CRC) is the third most common epithelial malignancy in the world. Since CRC develops slowly from removable precancerous lesions, detection of the lesion at an early stage by regular health examinations can reduce the incidence and mortality of this malignancy. Colonoscopy significantly improves the detection rate of CRC, but the examination is expensive and inconvenient. Therefore, we need novel biomarkers that are non-invasive to enable us to detect CRC quite early. A number of validation studies have been conducted to evaluate genetic, epigenetic or protein markers for identification in the stool and/or serum. Currently, the fecal occult blood test is the most widely used method of screening for CRC. However, advances in genomics and proteomics will lead to the discovery of novel non-invasive biomarkers.
Keywords: biomarkers; colorectal cancer; fecal biomarkers; genomic and epigenetic biomarkers; serum biomarkers; microRNA
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MDPI and ACS Style

Tanaka, T.; Tanaka, M.; Tanaka, T.; Ishigamori, R. Biomarkers for Colorectal Cancer. Int. J. Mol. Sci. 2010, 11, 3209-3225.

AMA Style

Tanaka T, Tanaka M, Tanaka T, Ishigamori R. Biomarkers for Colorectal Cancer. International Journal of Molecular Sciences. 2010; 11(9):3209-3225.

Chicago/Turabian Style

Tanaka, Takuji; Tanaka, Mayu; Tanaka, Takahiro; Ishigamori, Rikako. 2010. "Biomarkers for Colorectal Cancer." Int. J. Mol. Sci. 11, no. 9: 3209-3225.


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