Next Article in Journal
Energetics of Glucose Metabolism: A Phenomenological Approach to Metabolic Network Modeling
Next Article in Special Issue
Biological Properties of Iron Oxide Nanoparticles for Cellular and Molecular Magnetic Resonance Imaging
Previous Article in Journal
Hypoxic and Highly Angiogenic Non-Tumor Tissues Surrounding Hepatocellular Carcinoma: The ‘Niche’ of Endothelial Progenitor Cells
Previous Article in Special Issue
Paramagnetic Liposome Nanoparticles for Cellular and Tumour Imaging
Article Menu

Export Article

Open AccessArticle
Int. J. Mol. Sci. 2010, 11(8), 2910-2920; doi:10.3390/ijms11082910

Construction of Cardiac Tissue Rings Using a Magnetic Tissue Fabrication Technique

Department of Chemical Engineering, Faculty of Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan
*
Author to whom correspondence should be addressed.
Received: 22 April 2010 / Revised: 26 July 2010 / Accepted: 2 August 2010 / Published: 10 August 2010
(This article belongs to the Special Issue Magnetic Nanoparticles)
View Full-Text   |   Download PDF [314 KB, uploaded 19 June 2014]   |  

Abstract

Here we applied a magnetic force-based tissue engineering technique to cardiac tissue fabrication. A mixture of extracellular matrix precursor and cardiomyocytes labeled with magnetic nanoparticles was added into a well containing a central polycarbonate cylinder. With the use of a magnet, the cells were attracted to the bottom of the well and allowed to form a cell layer. During cultivation, the cell layer shrank towards the cylinder, leading to the formation of a ring-shaped tissue that possessed a multilayered cell structure and contractile properties. These results indicate that magnetic tissue fabrication is a promising approach for cardiac tissue engineering. View Full-Text
Keywords: cardiac tissue engineering; cardiomyocytes; magnetic nanoparticle; magnetic force cardiac tissue engineering; cardiomyocytes; magnetic nanoparticle; magnetic force
Figures

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Akiyama, H.; Ito, A.; Sato, M.; Kawabe, Y.; Kamihira, M. Construction of Cardiac Tissue Rings Using a Magnetic Tissue Fabrication Technique. Int. J. Mol. Sci. 2010, 11, 2910-2920.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top