Int. J. Mol. Sci. 2009, 10(9), 3776-3792; doi:10.3390/ijms10093776
Review

The Reversal of Drug-Resistance in Tumors Using a Drug-Carrying Nanoparticular System

1,#email, 2,#email, 2email, 3email, 4email and 2,* email
Received: 4 August 2009; Accepted: 26 August 2009 / Published: 31 August 2009
(This article belongs to the Section Material Sciences and Nanotechnology)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Medical applications of nanoparticular systems have attracted considerable attention because of their potential use in therapeutic targeting of disease tissues and their lower level of toxicity against healthy tissue, relative to traditional pharmaceutical drugs. The use of nanoparticular systems has been shown to overcome the limitations of most anticancer drugs in clinical applications. In particular, the improved performance of smarted nanoparticular system for solving the drug resistance problems that typically interrupt tumor treatment has provided a promising strategy for successful tumor chemotherapy. This review highlights recent studies that have examined the therapeutic effect of nanoparticular systems on drug-resistant tumors and presents insight on how they work.
Keywords: multi-drug resistance; nanoparticle; tumor treatment; drug delivery system
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MDPI and ACS Style

Oh, K.T.; Baik, H.J.; Lee, A.H.; Oh, Y.T.; Youn, Y.S.; Lee, E.S. The Reversal of Drug-Resistance in Tumors Using a Drug-Carrying Nanoparticular System. Int. J. Mol. Sci. 2009, 10, 3776-3792.

AMA Style

Oh KT, Baik HJ, Lee AH, Oh YT, Youn YS, Lee ES. The Reversal of Drug-Resistance in Tumors Using a Drug-Carrying Nanoparticular System. International Journal of Molecular Sciences. 2009; 10(9):3776-3792.

Chicago/Turabian Style

Oh, Kyung T.; Baik, Hye J.; Lee, A H.; Oh, Young T.; Youn, Yu S.; Lee, Eun S. 2009. "The Reversal of Drug-Resistance in Tumors Using a Drug-Carrying Nanoparticular System." Int. J. Mol. Sci. 10, no. 9: 3776-3792.

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