Next Article in Journal
The Hunt for Natural Skin Whitening Agents
Previous Article in Journal
Microwave Effect for Glycosylation Promoted by Solid Super Acid in Supercritical Carbon Dioxide
Previous Article in Special Issue
Analysis of Cooperativity by Isothermal Titration Calorimetry
Article Menu

Export Article

Open AccessArticle
Int. J. Mol. Sci. 2009, 10(12), 5296-5325; doi:10.3390/ijms10125296

On the Physical Meaning of the Isothermal Titration Calorimetry Measurements in Calorimeters with Full Cells

1
Laboratoire de Thermodynamique des Solutions et des Polymères Université Blaise Pascal, 24, Avenue des Landais, Clermont Ferrand, 63177 Aubière Cedex, France
2
Research and Development Branch on Flow Assurance, Mexican Institute of Petroleum, Eje Central Lazaro Cardenas 152, Col. San Bartolo Atepehuacan, Mexico City 07730, Mexico
*
Author to whom correspondence should be addressed.
Received: 7 October 2009 / Revised: 6 November 2009 / Accepted: 8 December 2009 / Published: 9 December 2009
(This article belongs to the Special Issue Isothermal Titration Calorimetry)
View Full-Text   |   Download PDF [188 KB, uploaded 19 June 2014]   |  

Abstract

We have performed a detailed study of the thermodynamics of the titration Process in an isothermal titration calorimeter with full cells. We show that the relationship between the enthalpy and the heat measured is better described in terms of the equation ΔH = Winj + Q (where Winj is the work necessary to carry out the titration) than in terms of ΔH = Q. Moreover, we show that the heat of interaction between two components is related to the partial enthalpy of interaction at infinite dilution of the titrant component, as well as to its partial volume of interaction at infinite dilution.
Keywords: isothermal titration calorimetry; ITC; calorimetry; thermodynamics; infinite dilution; binding; partial properties; enthalpy; heat isothermal titration calorimetry; ITC; calorimetry; thermodynamics; infinite dilution; binding; partial properties; enthalpy; heat
Figures

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Grolier, J.-P.E.; Del Río, J.M. On the Physical Meaning of the Isothermal Titration Calorimetry Measurements in Calorimeters with Full Cells. Int. J. Mol. Sci. 2009, 10, 5296-5325.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top