- freely available
The Hunt for Natural Skin Whitening Agents
AbstractSkin whitening products are commercially available for cosmetic purposes in order to obtain a lighter skin appearance. They are also utilized for clinical treatment of pigmentary disorders such as melasma or postinflammatory hyperpigmentation. Whitening agents act at various levels of melanin production in the skin. Many of them are known as competitive inhibitors of tyrosinase, the key enzyme in melanogenesis. Others inhibit the maturation of this enzyme or the transport of pigment granules (melanosomes) from melanocytes to surrounding keratinocytes. In this review we present an overview of (natural) whitening products that may decrease skin pigmentation by their interference with the pigmentary processes.
Share & Cite This Article
Smit, N.; Vicanova, J.; Pavel, S. The Hunt for Natural Skin Whitening Agents. Int. J. Mol. Sci. 2009, 10, 5326-5349.View more citation formats
Smit N, Vicanova J, Pavel S. The Hunt for Natural Skin Whitening Agents. International Journal of Molecular Sciences. 2009; 10(12):5326-5349.Chicago/Turabian Style
Smit, Nico; Vicanova, Jana; Pavel, Stan. 2009. "The Hunt for Natural Skin Whitening Agents." Int. J. Mol. Sci. 10, no. 12: 5326-5349.