Next Article in Journal
First-Principles Molecular Dynamics Calculations of the Equation of State for Tantalum
Previous Article in Journal
Modelling Catalyst Surfaces Using DFT Cluster Calculations
Article Menu

Export Article

Open AccessArticle
Int. J. Mol. Sci. 2009, 10(10), 4330-4341; doi:10.3390/ijms10104330

Extraction of Teucrium manghuaense and Evaluation of the Bioactivity of Its Extract

1
Analysis and Test Center of Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China
2
Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China
3
Hainan Branch Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Wanning 571533, China
*
Author to whom correspondence should be addressed.
Received: 15 July 2009 / Revised: 9 September 2009 / Accepted: 24 September 2009 / Published: 9 October 2009
(This article belongs to the Section Biochemistry, Molecular Biology and Biophysics)
View Full-Text   |   Download PDF [258 KB, uploaded 19 June 2014]   |  

Abstract

The ethanol extract of Teucrium manghuaense grown in Hainan province (China) was analysed by GC and GC/MS. Of the constituents 84–96% were identified on the basis of their GC retention times and their mass spectra in regard to authentic compounds. The results revealed that it contained 9-methyl-9-azabicyclo[4.2.1]nonane (7.43%), 2-methylpyrrolidine (19.42%), 3,7,11,15-tetramethyl-2-hexadecen-1-ol (10.84%), and squalene (28.55%), as major components, constituting 66.24% of the extract. The chemical characterization of the ethanol extract by GC/MS also allowed identification of 1-octen-3-one (3.41%), 2-pentyl-piperidine (2.25%), 1-(2-methyl-1-propenyl)-piperidine (4.63%), 2,2'-diethoxy-5,5'-bi-1-pyrroline (0.41%), (Z,Z,Z)-9,12,15-octadecatrieniic acid, 2,3-dihydroxypropyl ester (1.56%), vitamin E (2.95%) and stigmasterol (1.39%). Finally, the antioxidant and anti-tumor activities of the ethanol extract have been evaluated. Results show that the extract of Teucrium manghuaense leaf possesses strong DPPH-, hydroxyl radical scavenging activity and anti-tumor activity.
Keywords: Teucrium manghuaense; extraction; squalene; GC-MS; antioxidant; anti-tumor Teucrium manghuaense; extraction; squalene; GC-MS; antioxidant; anti-tumor
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Yin, G.; Zeng, H.; He, M.; Wang, M. Extraction of Teucrium manghuaense and Evaluation of the Bioactivity of Its Extract. Int. J. Mol. Sci. 2009, 10, 4330-4341.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top