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Molecules 2004, 9(8), 694-704; doi:10.3390/90800694

Synthesis of Some Novel 11b-Substituted Pyrimido[6,1-a]-isoquinoline Derivatives

* ,  and
Department of Organic Chemistry, University of Plovdiv, 24 "Tsar Asen" str., 4000 Plovdiv, Bulgaria
* Author to whom correspondence should be addressed.
Received: 17 June 2004 / Accepted: 29 June 2004 / Published: 31 July 2004
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A series of novel 11b-substituted 1,6,7,11b-tetrahydropyrimido[6,1-a]- isoquinoline-2,4-diones and 4-thioxo-1,3,4,6,7,11b-hexahydropyrimido[6,1-a]isoquinolin-2- ones were synthesized, utilizing two alternative strategies for ring closure of tetrahydroisoquinoline intermediates obtained from N-phenethyl enaminones
Keywords: Tetrahydroisoquinolines; pyrimido[6; 1-a]isoquinolines; enaminones. Tetrahydroisoquinolines; pyrimido[6; 1-a]isoquinolines; enaminones.
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Angelov, P.A.; Ivanov, I.I.; Venkov, A.P. Synthesis of Some Novel 11b-Substituted Pyrimido[6,1-a]-isoquinoline Derivatives. Molecules 2004, 9, 694-704.

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