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Molecules 2004, 9(8), 694-704; doi:10.3390/90800694

Synthesis of Some Novel 11b-Substituted Pyrimido[6,1-a]-isoquinoline Derivatives

* ,  and
Department of Organic Chemistry, University of Plovdiv, 24 "Tsar Asen" str., 4000 Plovdiv, Bulgaria
* Author to whom correspondence should be addressed.
Received: 17 June 2004 / Accepted: 29 June 2004 / Published: 31 July 2004
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A series of novel 11b-substituted 1,6,7,11b-tetrahydropyrimido[6,1-a]- isoquinoline-2,4-diones and 4-thioxo-1,3,4,6,7,11b-hexahydropyrimido[6,1-a]isoquinolin-2- ones were synthesized, utilizing two alternative strategies for ring closure of tetrahydroisoquinoline intermediates obtained from N-phenethyl enaminones
Keywords: Tetrahydroisoquinolines; pyrimido[6; 1-a]isoquinolines; enaminones. Tetrahydroisoquinolines; pyrimido[6; 1-a]isoquinolines; enaminones.
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Angelov, P.A.; Ivanov, I.I.; Venkov, A.P. Synthesis of Some Novel 11b-Substituted Pyrimido[6,1-a]-isoquinoline Derivatives. Molecules 2004, 9, 694-704.

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