Next Article in Journal
“Seek, and ye shall find” (Matthew 7:7)
Previous Article in Journal
Synthesis of Some Novel 11b-Substituted Pyrimido[6,1-a]-isoquinoline Derivatives
Molecules 2004, 9(8), 705-712; doi:10.3390/90800705

Synthesis of Benzoxazinone Derivatives: A New Route to 2 (N Phthaloylmethyl)-4H-3,1-benzoxazin-4-one

 and *
Department of Chemistry, Payamnoor University of Golpayegan, Golpayegan, Iran
* Author to whom correspondence should be addressed.
Received: 8 May 2004 / Revised: 29 July 2004 / Accepted: 30 July 2004 / Published: 31 July 2004
View Full-Text   |   Download PDF [157 KB, uploaded 18 June 2014]   |  


A new method has been designed to prepare the known benzoxazinone derivative 2-(N-phthaloylmethyl)-4H-3,1-benzoxazin-4-one (4). The acyl chloride derivative N-phthaloylglycine reacts with anthranilic acid in chloroform, in the presence of triethylamine, to give an intermediate that is then reacted with cyanuric chloride, used as a cyclization agent, to produce the benzoxazinone derivative.
Keywords: Benzoxazinone; Quinazolones; Cyanuric acid Benzoxazinone; Quinazolones; Cyanuric acid
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote |
MDPI and ACS Style

Shariat, M.; Abdollahi, S. Synthesis of Benzoxazinone Derivatives: A New Route to 2 (N Phthaloylmethyl)-4H-3,1-benzoxazin-4-one. Molecules 2004, 9, 705-712.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here


[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert