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Molecules 2004, 9(8), 705-712; doi:10.3390/90800705

Synthesis of Benzoxazinone Derivatives: A New Route to 2 (N Phthaloylmethyl)-4H-3,1-benzoxazin-4-one

 and *
Department of Chemistry, Payamnoor University of Golpayegan, Golpayegan, Iran
* Author to whom correspondence should be addressed.
Received: 8 May 2004 / Revised: 29 July 2004 / Accepted: 30 July 2004 / Published: 31 July 2004
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A new method has been designed to prepare the known benzoxazinone derivative 2-(N-phthaloylmethyl)-4H-3,1-benzoxazin-4-one (4). The acyl chloride derivative N-phthaloylglycine reacts with anthranilic acid in chloroform, in the presence of triethylamine, to give an intermediate that is then reacted with cyanuric chloride, used as a cyclization agent, to produce the benzoxazinone derivative.
Keywords: Benzoxazinone; Quinazolones; Cyanuric acid Benzoxazinone; Quinazolones; Cyanuric acid
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Shariat, M.; Abdollahi, S. Synthesis of Benzoxazinone Derivatives: A New Route to 2 (N Phthaloylmethyl)-4H-3,1-benzoxazin-4-one. Molecules 2004, 9, 705-712.

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