Synthesis of Benzoxazinone Derivatives: A New Route to 2 (N Phthaloylmethyl)-4H-3,1-benzoxazin-4-one

doi:10.3390/90800705

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Molecules 2004, 9(8), 705-712; doi:10.3390/90800705

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Synthesis of Benzoxazinone Derivatives: A New Route to 2 (N Phthaloylmethyl)-4H-3,1-benzoxazin-4-one

Mehdi Shariat and Sohrab Abdollahi*

Department of Chemistry, Payamnoor University of Golpayegan, Golpayegan, Iran

* Author to whom correspondence should be addressed.

Received: 8 May 2004; in revised form: 29 July 2004 / Accepted: 30 July 2004 / Published: 31 July 2004

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Abstract: A new method has been designed to prepare the known benzoxazinone derivative 2-(N-phthaloylmethyl)-4H-3,1-benzoxazin-4-one (4). The acyl chloride derivative N-phthaloylglycine reacts with anthranilic acid in chloroform, in the presence of triethylamine, to give an intermediate that is then reacted with cyanuric chloride, used as a cyclization agent, to produce the benzoxazinone derivative.

Keywords: Benzoxazinone; Quinazolones; Cyanuric acid

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MDPI and ACS Style

Shariat, M.; Abdollahi, S. Synthesis of Benzoxazinone Derivatives: A New Route to 2 (N Phthaloylmethyl)-4H-3,1-benzoxazin-4-one. Molecules 2004, 9, 705-712.

AMA Style

Shariat M, Abdollahi S. Synthesis of Benzoxazinone Derivatives: A New Route to 2 (N Phthaloylmethyl)-4H-3,1-benzoxazin-4-one. Molecules. 2004; 9(8):705-712.

Chicago/Turabian Style

Shariat, Mehdi; Abdollahi, Sohrab. 2004. "Synthesis of Benzoxazinone Derivatives: A New Route to 2 (N Phthaloylmethyl)-4H-3,1-benzoxazin-4-one." Molecules 9, no. 8: 705-712.

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