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Molecules 2004, 9(8), 705-712; doi:10.3390/90800705
Article

Synthesis of Benzoxazinone Derivatives: A New Route to 2 (N Phthaloylmethyl)-4H-3,1-benzoxazin-4-one

 and *
Department of Chemistry, Payamnoor University of Golpayegan, Golpayegan, Iran
* Author to whom correspondence should be addressed.
Received: 8 May 2004 / Revised: 29 July 2004 / Accepted: 30 July 2004 / Published: 31 July 2004
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Abstract

A new method has been designed to prepare the known benzoxazinone derivative 2-(N-phthaloylmethyl)-4H-3,1-benzoxazin-4-one (4). The acyl chloride derivative N-phthaloylglycine reacts with anthranilic acid in chloroform, in the presence of triethylamine, to give an intermediate that is then reacted with cyanuric chloride, used as a cyclization agent, to produce the benzoxazinone derivative.
Keywords: Benzoxazinone; Quinazolones; Cyanuric acid Benzoxazinone; Quinazolones; Cyanuric acid
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Shariat, M.; Abdollahi, S. Synthesis of Benzoxazinone Derivatives: A New Route to 2 (N Phthaloylmethyl)-4H-3,1-benzoxazin-4-one. Molecules 2004, 9, 705-712.

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