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Molecules 2004, 9(7), 609-616; doi:10.3390/90700609
Article

Syntheses of Quinazoline-2,4-dione Alkaloids and Analogues from Mexican Zanthoxylum Species †

* ,  and
Centro de Graduados e Investigación, Instituto Tecnológico de Tijuana, Apartado Postal 1166. 22000. Tijuana, B.C. México
* Author to whom correspondence should be addressed.
Received: 25 March 2004 / Accepted: 26 April 2004 / Published: 30 June 2004
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Abstract

Quinazolinone and quinazolinedione derivatives are of considerable interest due to their wide array of pharmacological properties. In this paper we report the synthesis of ten quinazolinediones. The previous isolation of two of these compounds, namely 1-methyl-3-(2'-phenylethyl)-1H,3H-quinazoline-2,4-dione and 1-methyl-3-[2'-(4'- methoxyphenyl)ethyl]-lH,3H-quinazoline-2,4-dione, from the seed husks of Mexican Zanthoxylum species has been reported
Keywords: Quinazoline-2; 4-dione; alkaloids; triphosgene; anti-hypertensive activity. Quinazoline-2; 4-dione; alkaloids; triphosgene; anti-hypertensive activity.
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Rivero, I.A.; Espinoza, K.; Somanathan, R. Syntheses of Quinazoline-2,4-dione Alkaloids and Analogues from Mexican Zanthoxylum Species †. Molecules 2004, 9, 609-616.

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