Syntheses of Quinazoline-2,4-dione Alkaloids and Analogues from Mexican Zanthoxylum Species †

doi:10.3390/90700609

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Molecules 2004, 9(7), 609-616; doi:10.3390/90700609

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Syntheses of Quinazoline-2,4-dione Alkaloids and Analogues from Mexican Zanthoxylum Species †

I. A. Rivero* , K. Espinoza and R. Somanathan

Centro de Graduados e Investigación, Instituto Tecnológico de Tijuana, Apartado Postal 1166. 22000. Tijuana, B.C. México

* Author to whom correspondence should be addressed.

Received: 25 March 2004 / Accepted: 26 April 2004 / Published: 30 June 2004

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Abstract: Quinazolinone and quinazolinedione derivatives are of considerable interest due to their wide array of pharmacological properties. In this paper we report the synthesis of ten quinazolinediones. The previous isolation of two of these compounds, namely 1-methyl-3-(2'-phenylethyl)-1H,3H-quinazoline-2,4-dione and 1-methyl-3-[2'-(4'- methoxyphenyl)ethyl]-lH,3H-quinazoline-2,4-dione, from the seed husks of Mexican Zanthoxylum species has been reported

Keywords: Quinazoline-2; 4-dione; alkaloids; triphosgene; anti-hypertensive activity.

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MDPI and ACS Style

Rivero, I.A.; Espinoza, K.; Somanathan, R. Syntheses of Quinazoline-2,4-dione Alkaloids and Analogues from Mexican Zanthoxylum Species †. Molecules 2004, 9, 609-616.

AMA Style

Rivero IA, Espinoza K, Somanathan R. Syntheses of Quinazoline-2,4-dione Alkaloids and Analogues from Mexican Zanthoxylum Species †. Molecules. 2004; 9(7):609-616.

Chicago/Turabian Style

Rivero, I. A.; Espinoza, K.; Somanathan, R. 2004. "Syntheses of Quinazoline-2,4-dione Alkaloids and Analogues from Mexican Zanthoxylum Species †." Molecules 9, no. 7: 609-616.

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