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Molecules 2004, 9(6), 498-512; doi:10.3390/90600498
Article

Synthesis of Pyran and Pyranone Natural Products

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Received: 25 March 2004 / Accepted: 5 April 2004 / Published: 31 May 2004
(This article belongs to the Special Issue RACI 2003 symposium)
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Abstract

An overview of the synthesis of the fungal metabolites (+)-dermolactone, (–)- semixanthomegnin, (+)- and (–)-mellein, (–)-ochratoxin α, (–)-(1R,3S)-thysanone, the enantiopure ventiloquinones L, E and G, and 8-desmethyleleutherin from a common chiral intermediate, is presented. Further methodology leading potentially toward extended quinones such as (3S,3'S)-xylindein is also outlined.
Keywords: Stereospecific synthesis; fungal metabolites; quinones; isochromanones. Stereospecific synthesis; fungal metabolites; quinones; isochromanones.
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Donner, C.D.; Gill, M.; Tewierik, L.M. Synthesis of Pyran and Pyranone Natural Products. Molecules 2004, 9, 498-512.

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