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Molecules 2004, 9(6), 513-519; doi:10.3390/90600513
Article

Synthesis and Characterisation of Macrocyclic Diamino Chiral Crown Ethers

*  and
Received: 4 March 2004; Accepted: 10 March 2004 / Published: 31 May 2004
(This article belongs to the Special Issue RACI 2003 symposium)
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Abstract: A benign and efficient synthesis of chiral macrocyclic ‘aza-crown’ ethers of varying ring size is reported. The synthesis involves a Schiff base condensation of ether linked dialdehydes of varying chain length and (1R,2R)-(–)-1,2-diaminocyclohexane under mild conditions to yield the macrocycles, which are subsequently reduced to yield the diamino analogues.
Keywords: Chiral diamino macrocycles; ether linked dialdehydes Chiral diamino macrocycles; ether linked dialdehydes
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Correa, W.H.; Scott, J.L. Synthesis and Characterisation of Macrocyclic Diamino Chiral Crown Ethers. Molecules 2004, 9, 513-519.

AMA Style

Correa WH, Scott JL. Synthesis and Characterisation of Macrocyclic Diamino Chiral Crown Ethers. Molecules. 2004; 9(6):513-519.

Chicago/Turabian Style

Correa, Waldo H.; Scott, Janet L. 2004. "Synthesis and Characterisation of Macrocyclic Diamino Chiral Crown Ethers." Molecules 9, no. 6: 513-519.



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