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Molecules 2004, 9(3), 158-163; doi:10.3390/90300158
Article

The Synthesis of Dicationic Extended Bis-Benzimidazoles

1, 2 and 1,*
1 Department of Chemistry Georgia State University, Atlanta, Georgia 30303, USA 2 Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, Alabama 36849, USA
* Author to whom correspondence should be addressed.
Received: 17 January 2004 / Revised: 26 January 2004 / Accepted: 27 January 2004 / Published: 28 February 2004
(This article belongs to the Special Issue Biologically Relevant Heterocyclic Compounds)
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Abstract

The synthesis of extended dicationic bis-benzimidazoles starting from trans-1,2-bis(4-cyanophenyl)ethene and trans-1,2-bis(4-cyanophenyl)cyclopropane is reported. The target diamidines show significant in vitro activity against B. subtilis.
Keywords: DIBAL reduction; benzimidazoles; amidines; Bacillus subtilis. DIBAL reduction; benzimidazoles; amidines; Bacillus subtilis.
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Kang, Z.; Dykstra, C.C.; Boykin, D.W. The Synthesis of Dicationic Extended Bis-Benzimidazoles. Molecules 2004, 9, 158-163.

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