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The Synthesis of Dicationic Extended Bis-Benzimidazoles
Department of Chemistry Georgia State University, Atlanta, Georgia 30303, USA
Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, Alabama 36849, USA
* Author to whom correspondence should be addressed.
Received: 17 January 2004; in revised form: 26 January 2004 / Accepted: 27 January 2004 / Published: 28 February 2004
Abstract: The synthesis of extended dicationic bis-benzimidazoles starting from trans-1,2-bis(4-cyanophenyl)ethene and trans-1,2-bis(4-cyanophenyl)cyclopropane is reported. The target diamidines show significant in vitro activity against B. subtilis.
Keywords: DIBAL reduction; benzimidazoles; amidines; Bacillus subtilis.
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Kang, Z.; Dykstra, C.C.; Boykin, D.W. The Synthesis of Dicationic Extended Bis-Benzimidazoles. Molecules 2004, 9, 158-163.
Kang Z, Dykstra CC, Boykin DW. The Synthesis of Dicationic Extended Bis-Benzimidazoles. Molecules. 2004; 9(3):158-163.
Kang, Zhijan; Dykstra, Christine C.; Boykin, David W. 2004. "The Synthesis of Dicationic Extended Bis-Benzimidazoles." Molecules 9, no. 3: 158-163.