Molecules 2004, 9(10), 894-901; doi:10.3390/91000894
Article

Fused Heterocycles: Synthesis of Some New Imidazo[1,2-a]- pyridine Derivatives

Istanbul University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 30416, Istanbul, Turkey
* Author to whom correspondence should be addressed.
Received: 4 August 2004; Accepted: 13 September 2004 / Published: 30 September 2004
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Abstract: Some new thiazolidines and spirothiazolidines derived from hydrazones of2-methylimidazo[1,2-a]pyridine-3-carboxylic acid hydrazide, a bioisosteric derivative ofisoniazid, were synthesized and characterized by analytical, IR, 1H- and 13C-NMR andmass spectral data. Some of the newly synthesized compounds were screened for theirantimycobacterial activities. None of the tested compounds showed significant in vitroantituberculous activity at 6.25 μg/mL (MIC rifampin 0.031 μg/mL).
Keywords: Imidazo[1; 2-a]pyridine; hydrazones; thiazolidines; spirothiazolidines; antituberculous activity.

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MDPI and ACS Style

Kasimogullari, B.O.; Cesur, Z. Fused Heterocycles: Synthesis of Some New Imidazo[1,2-a]- pyridine Derivatives. Molecules 2004, 9, 894-901.

AMA Style

Kasimogullari BO, Cesur Z. Fused Heterocycles: Synthesis of Some New Imidazo[1,2-a]- pyridine Derivatives. Molecules. 2004; 9(10):894-901.

Chicago/Turabian Style

Kasimogullari, Birgul O.; Cesur, Zafer. 2004. "Fused Heterocycles: Synthesis of Some New Imidazo[1,2-a]- pyridine Derivatives." Molecules 9, no. 10: 894-901.

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