Molecules 2004, 9(10), 849-859; doi:10.3390/91000849
Article

Unexpected Hydrazinolysis Behaviour of 1-Chloro-4-methyl-5H-pyridazino[4,5-b]indole and a Convenient Synthesis of New [1,2,4]-Triazolo[4’,3’:1,6]pyridazino[4,5-b]indoles

1, 1, 2,* email and 2
Received: 8 June 2004; Accepted: 18 June 2004 / Published: 30 September 2004
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Reaction of the title compound with hydrazine in the presence of air gives the 1-unsubstituted parent system via oxidative dehydrazination of the 1-hydrazino intermediate. The latter can be obtained in high yield by carrying out the hydrazinolysis step under inert gas, and it is smoothly converted into [1,2,4]-triazolo[4’,3’:1,6]pyridazino[4,5- b]indoles.
Keywords: Oxidative dehydrazination; pyridazine; indole; triazole.
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MDPI and ACS Style

El-Kashef, H.; Farghaly, A.A.H.; Haider, N.; Wobus, A. Unexpected Hydrazinolysis Behaviour of 1-Chloro-4-methyl-5H-pyridazino[4,5-b]indole and a Convenient Synthesis of New [1,2,4]-Triazolo[4’,3’:1,6]pyridazino[4,5-b]indoles. Molecules 2004, 9, 849-859.

AMA Style

El-Kashef H, Farghaly AAH, Haider N, Wobus A. Unexpected Hydrazinolysis Behaviour of 1-Chloro-4-methyl-5H-pyridazino[4,5-b]indole and a Convenient Synthesis of New [1,2,4]-Triazolo[4’,3’:1,6]pyridazino[4,5-b]indoles. Molecules. 2004; 9(10):849-859.

Chicago/Turabian Style

El-Kashef, Hussein; Farghaly, Abdelrahman A.H.; Haider, Norbert; Wobus, Andrea. 2004. "Unexpected Hydrazinolysis Behaviour of 1-Chloro-4-methyl-5H-pyridazino[4,5-b]indole and a Convenient Synthesis of New [1,2,4]-Triazolo[4’,3’:1,6]pyridazino[4,5-b]indoles." Molecules 9, no. 10: 849-859.

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