Synthesis of 2-(4-Methoxyphenyl)pyrrolo[2,1-d]pyrido[2,3-c]-[1,5]-thiazepin-3(2H)-one

doi:10.3390/80900678

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Molecules 2003, 8(9), 678-686; doi:10.3390/80900678

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Synthesis of 2-(4-Methoxyphenyl)pyrrolo[2,1-d]pyrido[2,3-c]-[1,5]-thiazepin-3(2H)-one

Eunsook Ma

College of Pharmacy, Catholic University of Daegu, Hayang, 712-702, Korea

Received: 7 March 2003; in revised form: 24 July 2003 / Accepted: 3 August 2003 / Published: 17 August 2003

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Abstract: 2-(4-Methoxyphenyl)pyrrolo[2,1-d]pyrido[2,3-c][1,5]thiazepin-3(2H)-one, a key intermediate in the synthesis of pyrrolopyridothiazepine derivatives, was synthesized from bis(4H-pyrrolo-3-pyridyl)disulfide and α-bromo-(4-methoxyphenyl) acetic acid ethyl ester in order to develop a novel calcium channel antagonist.

Keywords: Calcium channel antagonist; Thiation; Pyrrolopyridothiazepine; Intramolecular cyclization

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MDPI and ACS Style

Ma, E. Synthesis of 2-(4-Methoxyphenyl)pyrrolo[2,1-d]pyrido[2,3-c]-[1,5]-thiazepin-3(2H)-one. Molecules 2003, 8, 678-686.

AMA Style

Ma E. Synthesis of 2-(4-Methoxyphenyl)pyrrolo[2,1-d]pyrido[2,3-c]-[1,5]-thiazepin-3(2H)-one. Molecules. 2003; 8(9):678-686.

Chicago/Turabian Style

Ma, Eunsook. 2003. "Synthesis of 2-(4-Methoxyphenyl)pyrrolo[2,1-d]pyrido[2,3-c]-[1,5]-thiazepin-3(2H)-one." Molecules 8, no. 9: 678-686.

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