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Molecules 2003, 8(4), 381-391; doi:10.3390/80400381
Review

Synthesis and Aromatization of Hantzsch 1,4-Dihydropyridines under Microwave Irradiation. An Overview

1,2,*  and 1
1 Xavier University of Louisiana, College of Pharmacy, Division of Basic Pharmaceutical Sciences, 1 Drexel Drive, New Orleans, LA 70125, USA 2 Department of Organic Chemistry, University of Mons-Hainaut, 20 Place du Parc, B-7000 Mons, Belgium
* Author to whom correspondence should be addressed.
Received: 6 March 2003 / Revised: 2 April 2003 / Accepted: 3 April 2003 / Published: 30 April 2003
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Abstract

Domestic microwave ovens as well as laboratory reactors have been successfully employed to prepare dialkyl 1,4-dihydropyridine-3,5-dicarboxylates and to induce the synthesis of the corresponding aromatic derivatives. In that latter particular case, unexpected results have been reported.
Keywords: Aromatization; dihydropyridine; Hantzsch; microwave; oxidation; pyridine Aromatization; dihydropyridine; Hantzsch; microwave; oxidation; pyridine
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Vanden Eynde, J.J.; Mayence, A. Synthesis and Aromatization of Hantzsch 1,4-Dihydropyridines under Microwave Irradiation. An Overview. Molecules 2003, 8, 381-391.

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