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Molecules 2003, 8(4), 381-391; doi:10.3390/80400381
Review

Synthesis and Aromatization of Hantzsch 1,4-Dihydropyridines under Microwave Irradiation. An Overview

1,2,*  and 1
1 Xavier University of Louisiana, College of Pharmacy, Division of Basic Pharmaceutical Sciences, 1 Drexel Drive, New Orleans, LA 70125, USA 2 Department of Organic Chemistry, University of Mons-Hainaut, 20 Place du Parc, B-7000 Mons, Belgium
* Author to whom correspondence should be addressed.
Received: 6 March 2003 / Revised: 2 April 2003 / Accepted: 3 April 2003 / Published: 30 April 2003
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Abstract

Domestic microwave ovens as well as laboratory reactors have been successfully employed to prepare dialkyl 1,4-dihydropyridine-3,5-dicarboxylates and to induce the synthesis of the corresponding aromatic derivatives. In that latter particular case, unexpected results have been reported.
Keywords: Aromatization; dihydropyridine; Hantzsch; microwave; oxidation; pyridine Aromatization; dihydropyridine; Hantzsch; microwave; oxidation; pyridine
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Vanden Eynde, J.J.; Mayence, A. Synthesis and Aromatization of Hantzsch 1,4-Dihydropyridines under Microwave Irradiation. An Overview. Molecules 2003, 8, 381-391.

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