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Molecules 2003, 8(3), 342-348; doi:10.3390/80300342
Article

Synthesis of New Cyano-Substituted bis-Benzothiazolyl Arylfurans and Arylthiophenes

1, 1, 2 and 3,*
1 Faculty of Textile Technology, University of Zagreb, Pierottijeva 6, 10000 Zagreb, Croatia 2 Department of Chemistry and Center for Biotechnology and Drug Design, Georgia State University, Atlanta, Georgia 30303-3083, USA 3 Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulicev trg 20, 10000 Zagreb, Croatia
* Author to whom correspondence should be addressed.
Received: 12 December 2002 / Revised: 11 March 2003 / Accepted: 27 March 2003 / Published: 31 March 2003
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Abstract

The new compounds 2-[4-(6-cyanobenzothiazol-2-yl)phenyl]-5-(6-cyano-benzothiazol-2-yl)furan (6a) and 2-[4-(6-Cyanobenzothiazol-2-yl)phenyl]-5-(6-cyano-benzothiazol-2-yl)thiophene (6b) were synthesized by multi-step reactions from the corresponding 2-furan and 2-thiophene carboxaldehydes (route A), as well as from 2-furan and 2- thiophene carboxylic acids (route B). Route B involves one less step than route A, but the overall yields of the reactions are considerably lower.
Keywords: bis-Benzothiazole; 6-Cyanobenzothiazole; Furan; Thiophene bis-Benzothiazole; 6-Cyanobenzothiazole; Furan; Thiophene
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Racanè, L.; Tralić-Kulenović, V.; Boykin, D.W.; Karminski-Zamola, G. Synthesis of New Cyano-Substituted bis-Benzothiazolyl Arylfurans and Arylthiophenes. Molecules 2003, 8, 342-348.

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