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Molecules 2003, 8(3), 342-348; doi:10.3390/80300342

Synthesis of New Cyano-Substituted bis-Benzothiazolyl Arylfurans and Arylthiophenes

1, 1, 2 and 3,*
1 Faculty of Textile Technology, University of Zagreb, Pierottijeva 6, 10000 Zagreb, Croatia 2 Department of Chemistry and Center for Biotechnology and Drug Design, Georgia State University, Atlanta, Georgia 30303-3083, USA 3 Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulicev trg 20, 10000 Zagreb, Croatia
* Author to whom correspondence should be addressed.
Received: 12 December 2002 / Revised: 11 March 2003 / Accepted: 27 March 2003 / Published: 31 March 2003
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The new compounds 2-[4-(6-cyanobenzothiazol-2-yl)phenyl]-5-(6-cyano-benzothiazol-2-yl)furan (6a) and 2-[4-(6-Cyanobenzothiazol-2-yl)phenyl]-5-(6-cyano-benzothiazol-2-yl)thiophene (6b) were synthesized by multi-step reactions from the corresponding 2-furan and 2-thiophene carboxaldehydes (route A), as well as from 2-furan and 2- thiophene carboxylic acids (route B). Route B involves one less step than route A, but the overall yields of the reactions are considerably lower.
Keywords: bis-Benzothiazole; 6-Cyanobenzothiazole; Furan; Thiophene bis-Benzothiazole; 6-Cyanobenzothiazole; Furan; Thiophene
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Racanè, L.; Tralić-Kulenović, V.; Boykin, D.W.; Karminski-Zamola, G. Synthesis of New Cyano-Substituted bis-Benzothiazolyl Arylfurans and Arylthiophenes. Molecules 2003, 8, 342-348.

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