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Molecules 2003, 8(3), 342-348; doi:10.3390/80300342

Synthesis of New Cyano-Substituted bis-Benzothiazolyl Arylfurans and Arylthiophenes

Faculty of Textile Technology, University of Zagreb, Pierottijeva 6, 10000 Zagreb, Croatia
Department of Chemistry and Center for Biotechnology and Drug Design, Georgia State University, Atlanta, Georgia 30303-3083, USA
Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulicev trg 20, 10000 Zagreb, Croatia
Author to whom correspondence should be addressed.
Received: 12 December 2002 / Revised: 11 March 2003 / Accepted: 27 March 2003 / Published: 31 March 2003
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The new compounds 2-[4-(6-cyanobenzothiazol-2-yl)phenyl]-5-(6-cyano-benzothiazol-2-yl)furan (6a) and 2-[4-(6-Cyanobenzothiazol-2-yl)phenyl]-5-(6-cyano-benzothiazol-2-yl)thiophene (6b) were synthesized by multi-step reactions from the corresponding 2-furan and 2-thiophene carboxaldehydes (route A), as well as from 2-furan and 2- thiophene carboxylic acids (route B). Route B involves one less step than route A, but the overall yields of the reactions are considerably lower.
Keywords: bis-Benzothiazole; 6-Cyanobenzothiazole; Furan; Thiophene bis-Benzothiazole; 6-Cyanobenzothiazole; Furan; Thiophene
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Racanè, L.; Tralić-Kulenović, V.; Boykin, D.W.; Karminski-Zamola, G. Synthesis of New Cyano-Substituted bis-Benzothiazolyl Arylfurans and Arylthiophenes. Molecules 2003, 8, 342-348.

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