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Molecules 2003, 8(1), 186-192; doi:10.3390/80100186

Synthesis and Bioactivity of a-Aminophosphonates Containing Fluorine

* , , , ,  and
Research and Development Center of Fine Chemicals, Guizhou University, Guiyang, 550025, P.R. China
* Author to whom correspondence should be addressed.
Received: 1 January 2003 / Published: 31 January 2003
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Twenty-one a-aminophosphonates containing fluorine were synthesized by Mannich-type reactions. Their structures were established by elemental analysis, IR, 1H- NMR and MS. In field tests, some of these new compounds display high antiviral activity against the tobacco mosaic virus (TMV). The molecular geometry of compound 4f was determined by X-ray diffraction structure analysis.
Keywords: a-Aminophosphonates; synthesis; bioactivity a-Aminophosphonates; synthesis; bioactivity
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Song, B.-A.; Wu, Y.-L.; Yang, S.; Hu, D.-Y.; He, X.-Q.; Jin, L.-H. Synthesis and Bioactivity of a-Aminophosphonates Containing Fluorine. Molecules 2003, 8, 186-192.

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