Synthesis and Bioactivity of a-Aminophosphonates Containing Fluorine

doi:10.3390/80100186

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Molecules 2003, 8(1), 186-192; doi:10.3390/80100186

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Synthesis and Bioactivity of a-Aminophosphonates Containing Fluorine

Bao-An Song* , Yang-Lan Wu, Song Yang, De-Yu Hu, Xiang-Qiong He and Lin-Hong Jin

Research and Development Center of Fine Chemicals, Guizhou University, Guiyang, 550025, P.R. China

* Author to whom correspondence should be addressed.

Received: 1 January 2003 / Published: 31 January 2003

(This article belongs to the Special Issue Selected Papers from the International Symposium on Frontiers in Molecular Science (ISFMS 2002))

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Abstract: Twenty-one a-aminophosphonates containing fluorine were synthesized by Mannich-type reactions. Their structures were established by elemental analysis, IR, ¹H- NMR and MS. In field tests, some of these new compounds display high antiviral activity against the tobacco mosaic virus (TMV). The molecular geometry of compound 4f was determined by X-ray diffraction structure analysis.

Keywords: a-Aminophosphonates; synthesis; bioactivity

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MDPI and ACS Style

Song, B.-A.; Wu, Y.-L.; Yang, S.; Hu, D.-Y.; He, X.-Q.; Jin, L.-H. Synthesis and Bioactivity of a-Aminophosphonates Containing Fluorine. Molecules 2003, 8, 186-192.

AMA Style

Song B-A, Wu Y-L, Yang S, Hu D-Y, He X-Q, Jin L-H. Synthesis and Bioactivity of a-Aminophosphonates Containing Fluorine. Molecules. 2003; 8(1):186-192.

Chicago/Turabian Style

Song, Bao-An; Wu, Yang-Lan; Yang, Song; Hu, De-Yu; He, Xiang-Qiong; Jin, Lin-Hong. 2003. "Synthesis and Bioactivity of a-Aminophosphonates Containing Fluorine." Molecules 8, no. 1: 186-192.

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