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Molecules 2003, 8(1), 186-192; doi:10.3390/80100186

Synthesis and Bioactivity of a-Aminophosphonates Containing Fluorine

* , , , ,  and
Research and Development Center of Fine Chemicals, Guizhou University, Guiyang, 550025, P.R. China
* Author to whom correspondence should be addressed.
Received: 1 January 2003 / Published: 31 January 2003
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Twenty-one a-aminophosphonates containing fluorine were synthesized by Mannich-type reactions. Their structures were established by elemental analysis, IR, 1H- NMR and MS. In field tests, some of these new compounds display high antiviral activity against the tobacco mosaic virus (TMV). The molecular geometry of compound 4f was determined by X-ray diffraction structure analysis.
Keywords: a-Aminophosphonates; synthesis; bioactivity a-Aminophosphonates; synthesis; bioactivity
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Song, B.-A.; Wu, Y.-L.; Yang, S.; Hu, D.-Y.; He, X.-Q.; Jin, L.-H. Synthesis and Bioactivity of a-Aminophosphonates Containing Fluorine. Molecules 2003, 8, 186-192.

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