Molecules 2002, 7(8), 662-673; doi:10.3390/70800662
Article

NMR Detection of Isomers Arising from Restricted Rotation of the C-N Amide Bond of N-Formyl-o-toluidine and N,N’-bis-Formyl-o-tolidine

1,* email, 2, 3, 1, 1, 1 and 3
Received: 19 April 2002; in revised form: 28 July 2002 / Accepted: 13 August 2002 / Published: 31 August 2002
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Full and unambiguous assignment of all 1H- and 13C-NMR resonances of the isomers due to restricted C-N amide bond rotation of N-formyl-o-toluidine and N,N'-bis-formyl-o-tolidine in DMSO-d6 is reported. The cis-isomer predominates in the equilibrium mixture of both compounds as 1D-NOE difference experiments show.
Keywords: Amide bond; restricted rotation; 1H-NMR; 13C-NMR; NOE
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MDPI and ACS Style

Quintanilla-Licea, R.; Colunga-Valladares, J.F.; Caballero-Quintero, A.; Rodríguez-Padilla, C.; Tamez-Guerra, R.; Gómez-Flores, R.; Waksman, N. NMR Detection of Isomers Arising from Restricted Rotation of the C-N Amide Bond of N-Formyl-o-toluidine and N,N’-bis-Formyl-o-tolidine. Molecules 2002, 7, 662-673.

AMA Style

Quintanilla-Licea R, Colunga-Valladares JF, Caballero-Quintero A, Rodríguez-Padilla C, Tamez-Guerra R, Gómez-Flores R, Waksman N. NMR Detection of Isomers Arising from Restricted Rotation of the C-N Amide Bond of N-Formyl-o-toluidine and N,N’-bis-Formyl-o-tolidine. Molecules. 2002; 7(8):662-673.

Chicago/Turabian Style

Quintanilla-Licea, Ramiro; Colunga-Valladares, Juan F.; Caballero-Quintero, Adolfo; Rodríguez-Padilla, Cristina; Tamez-Guerra, Reyes; Gómez-Flores, Ricardo; Waksman, Noemí. 2002. "NMR Detection of Isomers Arising from Restricted Rotation of the C-N Amide Bond of N-Formyl-o-toluidine and N,N’-bis-Formyl-o-tolidine." Molecules 7, no. 8: 662-673.

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