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Molecules 2002, 7(7), 554-565; doi:10.3390/70700554
Article

Annellation of Triazole and Tetrazole Systems onto Pyrrolo[2,3-d]pyrimidines: Synthesis of Tetrazolo[1,5-c]-pyrrolo[3,2-e]-pyrimidines and Triazolo[1,5-c]pyrrolo-[3,2-e]pyrimidines as Potential Antibacterial Agents

*  and
Organic Syntheses Laboratory, M.G. Science Institute, Navrangpura, Ahmedabad 380 009, India
* Author to whom correspondence should be addressed.
Received: 5 May 2002 / Revised: 12 July 2002 / Accepted: 28 July 2002 / Published: 31 July 2002
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Abstract

Syntheses of several novel 4-chloropyrrolo[2,3-d]pyrimidines (1), 4-hydrazinopyrrolo[2,3-d]pyrimidines (2) and 3-amino-4-iminopyrrolo[2,3-d]pyrimidines (7) and their use in the synthesis of tetrazolo[1,5-c]pyrrolo[3,2-e]pyrimidines (3) and triazolo[1,5-c]pyrrolo[3,2-e]pyrimidines (4) required for biological screening are reported.
Keywords: Tetrazolopyrrolopyrimidines; triazolopyrrolopyrimidines; pyrrolo[2; 3-d]- pyrimidines; antibacterial activity Tetrazolopyrrolopyrimidines; triazolopyrrolopyrimidines; pyrrolo[2; 3-d]- pyrimidines; antibacterial activity
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Dave, C.G.; Shah, R.D. Annellation of Triazole and Tetrazole Systems onto Pyrrolo[2,3-d]pyrimidines: Synthesis of Tetrazolo[1,5-c]-pyrrolo[3,2-e]-pyrimidines and Triazolo[1,5-c]pyrrolo-[3,2-e]pyrimidines as Potential Antibacterial Agents. Molecules 2002, 7, 554-565.

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