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Molecules 2002, 7(11), 777-790; doi:10.3390/71100777
Article

A Synthesis of 6-(2,5-Dimethoxy-4-(2-aminopropyl)phenyl)-hexylthiol. A Ligand for Conjugation with Fluorescent Cadmium Selenide/Zinc Sulfide Core/Shell Nanocrystals and Biological Imaging

,  and *
The Department of Chemistry, Vanderbilt University, Station B, 351822, Nashville, Tennessee, 37235-1822, USA
* Author to whom correspondence should be addressed.
Received: 13 July 2002 / Revised: 27 November 2002 / Accepted: 27 November 2002 / Published: 30 November 2002
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Abstract

The synthesis of 6-(2,5-dimethoxy-4-(2-aminopropyl)phenyl)hexylthiol, an agonist with a very high affinity for the 5HT2A serotonin receptor subtype is reported. This agonist was designed to be attached to highly fluorescent cadmium selenide/zinc sulfide core/shells via a thiol at the end of a linker arm. This conjugate has applications in biological assays and biological imaging.
Keywords: Cadmium selenide / zinc sulfide / core/shells / 5HT2A / fluorescent imaging Cadmium selenide / zinc sulfide / core/shells / 5HT2A / fluorescent imaging
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Tomlinson, I.D.; Grey, J.L.; Rosenthal, S.J. A Synthesis of 6-(2,5-Dimethoxy-4-(2-aminopropyl)phenyl)-hexylthiol. A Ligand for Conjugation with Fluorescent Cadmium Selenide/Zinc Sulfide Core/Shell Nanocrystals and Biological Imaging. Molecules 2002, 7, 777-790.

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