Molecules 2002, 7(10), 767-776; doi:10.3390/71000767
Article

Amino Acid Based Synthesis of Chiral Long Chain Diamines and Tetramines

Laboratory of Organic Chemistry, Department of Chemistry, University of Athens, Panepistimiopolis, Athens 15771, Greece
* Author to whom correspondence should be addressed.
Published: 31 October 2002
PDF Full-text Download PDF Full-Text [127 KB, uploaded 3 October 2008 11:52 CEST]
Abstract: A method for the synthesis of long chain diamines and tetramines starting from natural α-amino acids is reported. Diamines and tetramines were prepared through the Wittig olefination reaction of N-protected amino aldehydes obtained from phenylalanine and lysine. A 1,2,17,18-tetramine was synthesized using (2S)-1-azido-2-[bis(tert-butoxycarbonyl)-amino]-5-oxopentane as key-intermediate compound.
Keywords: amino acids; amino aldehydes; diamines; tetramines; Wittig reaction

Article Statistics

Load and display the download statistics.

Citations to this Article

Cite This Article

MDPI and ACS Style

Loukas, V.; Markidis, T.; Kokotos, G. Amino Acid Based Synthesis of Chiral Long Chain Diamines and Tetramines. Molecules 2002, 7, 767-776.

AMA Style

Loukas V, Markidis T, Kokotos G. Amino Acid Based Synthesis of Chiral Long Chain Diamines and Tetramines. Molecules. 2002; 7(10):767-776.

Chicago/Turabian Style

Loukas, Vassilios; Markidis, Theodoros; Kokotos, George. 2002. "Amino Acid Based Synthesis of Chiral Long Chain Diamines and Tetramines." Molecules 7, no. 10: 767-776.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert