Synthesis of Heterocyclic Skeletons by the Reaction of N1-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides

doi:10.3390/70100096

This article is

freely available
re-usable

Molecules 2002, 7(1), 96-103; doi:10.3390/70100096

Article

Synthesis of Heterocyclic Skeletons by the Reaction of N¹-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides

Walid M. Fathalla and Pavel Pazdera*

Department of Organic Chemistry, Faculty of Science, Masaryk University, Brno, Czech Republic

* Author to whom correspondence should be addressed.

Received: 27 December 2001; in revised form: 24 January 2002 / Accepted: 24 January 2002 / Published: 30 January 2002

Download PDF Full-Text [91 KB, uploaded 2 October 2008 15:40 CEST]

Abstract: The reaction of N-(2-cyanophenyl)benzimidoyl chloride with reagents containing a thioamide moiety, i.e. thioacetamide, benzylthiourea, symmetrical dialkyl- and diarylthioureas gave different cyclic products: 3,1-benzothiazine, 1,3,5-benzotriazocine and quinazoline. The reaction pathways of prepared compounds are discussed.

Keywords: N-(2-cyanophenyl)benzimidoyl chloride; thioamide; 3; 1-benzo-thiazine; 1; 3; 5-benzotriazocine; quinazoline; imidoyl chlorides; N-imidoyl thioureas

Article Statistics

Click here to load and display the download statistics.

Cite This Article

MDPI and ACS Style

Fathalla, W.M.; Pazdera, P. Synthesis of Heterocyclic Skeletons by the Reaction of N¹-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides. Molecules 2002, 7, 96-103.

AMA Style

Fathalla WM, Pazdera P. Synthesis of Heterocyclic Skeletons by the Reaction of N¹-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides. Molecules. 2002; 7(1):96-103.

Chicago/Turabian Style

Fathalla, Walid M.; Pazdera, Pavel. 2002. "Synthesis of Heterocyclic Skeletons by the Reaction of N¹-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides." Molecules 7, no. 1: 96-103.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert