Next Article in Journal
An Investigation of the Reactions of Substituted Homoallylic Alcohols with Various Oxidation Reagents
Previous Article in Journal
Three-Component Halo Aldol Condensation of Thioacrylates with Aldehydes Mediated by Titanium (IV) Halide
Molecules 2002, 7(1), 96-103; doi:10.3390/70100096
Article

Synthesis of Heterocyclic Skeletons by the Reaction of N1-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides

 and *
Department of Organic Chemistry, Faculty of Science, Masaryk University, Brno, Czech Republic
* Author to whom correspondence should be addressed.
Received: 27 December 2001 / Revised: 24 January 2002 / Accepted: 24 January 2002 / Published: 30 January 2002
View Full-Text   |   Download PDF [91 KB, uploaded 18 June 2014]   |  

Abstract

The reaction of N-(2-cyanophenyl)benzimidoyl chloride with reagents containing a thioamide moiety, i.e. thioacetamide, benzylthiourea, symmetrical dialkyl- and diarylthioureas gave different cyclic products: 3,1-benzothiazine, 1,3,5-benzotriazocine and quinazoline. The reaction pathways of prepared compounds are discussed.
Keywords: N-(2-cyanophenyl)benzimidoyl chloride; thioamide; 3; 1-benzo-thiazine; 1; 3; 5-benzotriazocine; quinazoline; imidoyl chlorides; N-imidoyl thioureas N-(2-cyanophenyl)benzimidoyl chloride; thioamide; 3; 1-benzo-thiazine; 1; 3; 5-benzotriazocine; quinazoline; imidoyl chlorides; N-imidoyl thioureas
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
SciFeed

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote |
RIS
MDPI and ACS Style

Fathalla, W.M.; Pazdera, P. Synthesis of Heterocyclic Skeletons by the Reaction of N1-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides. Molecules 2002, 7, 96-103.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here

Comments

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert