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Molecules 2002, 7(1), 96-103; doi:10.3390/70100096

Synthesis of Heterocyclic Skeletons by the Reaction of N1-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides

Department of Organic Chemistry, Faculty of Science, Masaryk University, Brno, Czech Republic
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Received: 27 December 2001 / Revised: 24 January 2002 / Accepted: 24 January 2002 / Published: 30 January 2002
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Abstract

The reaction of N-(2-cyanophenyl)benzimidoyl chloride with reagents containing a thioamide moiety, i.e. thioacetamide, benzylthiourea, symmetrical dialkyl- and diarylthioureas gave different cyclic products: 3,1-benzothiazine, 1,3,5-benzotriazocine and quinazoline. The reaction pathways of prepared compounds are discussed. View Full-Text
Keywords: N-(2-cyanophenyl)benzimidoyl chloride; thioamide; 3; 1-benzo-thiazine; 1; 3; 5-benzotriazocine; quinazoline; imidoyl chlorides; N-imidoyl thioureas N-(2-cyanophenyl)benzimidoyl chloride; thioamide; 3; 1-benzo-thiazine; 1; 3; 5-benzotriazocine; quinazoline; imidoyl chlorides; N-imidoyl thioureas
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Fathalla, W.M.; Pazdera, P. Synthesis of Heterocyclic Skeletons by the Reaction of N1-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides. Molecules 2002, 7, 96-103.

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