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Molecules 2002, 7(1), 96-103; doi:10.3390/70100096
Article

Synthesis of Heterocyclic Skeletons by the Reaction of N1-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides

 and *
Department of Organic Chemistry, Faculty of Science, Masaryk University, Brno, Czech Republic
* Author to whom correspondence should be addressed.
Received: 27 December 2001 / Revised: 24 January 2002 / Accepted: 24 January 2002 / Published: 30 January 2002
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Abstract

The reaction of N-(2-cyanophenyl)benzimidoyl chloride with reagents containing a thioamide moiety, i.e. thioacetamide, benzylthiourea, symmetrical dialkyl- and diarylthioureas gave different cyclic products: 3,1-benzothiazine, 1,3,5-benzotriazocine and quinazoline. The reaction pathways of prepared compounds are discussed.
Keywords: N-(2-cyanophenyl)benzimidoyl chloride; thioamide; 3; 1-benzo-thiazine; 1; 3; 5-benzotriazocine; quinazoline; imidoyl chlorides; N-imidoyl thioureas N-(2-cyanophenyl)benzimidoyl chloride; thioamide; 3; 1-benzo-thiazine; 1; 3; 5-benzotriazocine; quinazoline; imidoyl chlorides; N-imidoyl thioureas
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Fathalla, W.M.; Pazdera, P. Synthesis of Heterocyclic Skeletons by the Reaction of N1-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides. Molecules 2002, 7, 96-103.

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