Molecules 2001, 6(7), 603-613; doi:10.3390/60700603
Article

Some Anilides of 2-Alkylthio- and 2-Chloro-6-Alkylthio-4-Pyridinecarboxylic Acids: Synthesis and Photosynthesis-Inhibiting Activity

1 Department of Medicinal Chemistry and Drug Control, Charles University, Faculty of Pharmacy, 500 05 Hradec Králové, Czech Republic 2 Institute of Chemistry, Faculty of Natural Sciences, Comenius University, Bratislava, Slovak Republic 3 Department of Inorganic and Organic Chemistry, Charles University, Faculty of Pharmacy, 500 05 Hradec Králové, Czech Republic
* Author to whom correspondence should be addressed.
Received: 16 February 2001; in revised form: 28 May 2001 / Accepted: 1 May 2001 / Published: 30 June 2001
PDF Full-text Download PDF Full-Text [135 KB, uploaded 6 October 2008 09:48 CEST]
Abstract: Many compounds containing a -CONH- group display photosynthesis inhibiting activity. Based on this structural feature, a group of anilides of 2-alkylthio-(1b-4f) or 2-chloro-6-alkylthio-4-pyridinecarboxylic acids (5a-6c) was synthesised. The prepared compounds were tested for their inhibition of the oxygen evolution rate (OER) in spinach chloroplasts. A quasi-parabolic dependence between photosynthesis-inhibiting activity and the lipophilicity of the compounds was determined for 1b-4f as well as for 5a-6c. The inhibitory activity of compounds 1b-4f was higher than that of 5a-6c for comparable lipophilicity values.
Keywords: 2-Alkylthio-4-pyridinecarboxylic acids; Anilides; Photosynthesis inhibition

Article Statistics

Load and display the download statistics.

Citations to this Article

Cite This Article

MDPI and ACS Style

Miletín, M.; Doležal, M.; Opletalová, V.; Hartl, J.; Král’ová, K.; Macháček, M. Some Anilides of 2-Alkylthio- and 2-Chloro-6-Alkylthio-4-Pyridinecarboxylic Acids: Synthesis and Photosynthesis-Inhibiting Activity. Molecules 2001, 6, 603-613.

AMA Style

Miletín M, Doležal M, Opletalová V, Hartl J, Král’ová K, Macháček M. Some Anilides of 2-Alkylthio- and 2-Chloro-6-Alkylthio-4-Pyridinecarboxylic Acids: Synthesis and Photosynthesis-Inhibiting Activity. Molecules. 2001; 6(7):603-613.

Chicago/Turabian Style

Miletín, Miroslav; Doležal, Martin; Opletalová, Veronika; Hartl, Jiří; Král’ová, Katarína; Macháček, Miloš. 2001. "Some Anilides of 2-Alkylthio- and 2-Chloro-6-Alkylthio-4-Pyridinecarboxylic Acids: Synthesis and Photosynthesis-Inhibiting Activity." Molecules 6, no. 7: 603-613.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert