Next Article in Journal
Molecular Polarizability of Sc and C (Fullerene and Graphite) Clusters
Previous Article in Journal
Synthesis of 2,4,6-Tris(4-N-isopropylamidinophenyl)pyrimidine trihydrochloride
Article Menu

Export Article

Open AccessArticle
Molecules 2001, 6(5), 481-495; doi:10.3390/60500481

Thermal Rearrangement of Allyl Substituted Unsymmetric 4H-1,2,4-Triazoles to the Corresponding 1H-1,2,4-triazoles

Department of Chemistry, Norwegian University of Science and Technology, N-7491 Trondheim, Norway
Author to whom correspondence should be addressed.
Received: 14 March 2001 / Revised: 26 April 2001 / Accepted: 26 April 2001 / Published: 30 April 2001
View Full-Text   |   Download PDF [77 KB, uploaded 18 June 2014]   |  


A series of neat 4-(2-alkenyl) substituted 5-methyl-3-phenyl-4H-1,2,4-triazoles were thermolyzed at 320 oC producing a rearrangement products, of which the regioisomeric 1- and 2-substituted triazoles were the main products. The group migrations were rationalized in terms of consecutive SN2-type reactions. This mechanism was supported by a study of the alkylations of the triazoles which gave similar product mixtures. 4-(2-alkenyl) substituted 3-phenyl-4H-1,2,4-triazoles, on the other hand, gave predominantly elimination products. View Full-Text
Keywords: Thermolysis; 1; 2; 4-triazole; rearrangement Thermolysis; 1; 2; 4-triazole; rearrangement

Figure 1

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Jørgensen, K.B.; Olsen, R.B.; Carlsen, P.H. Thermal Rearrangement of Allyl Substituted Unsymmetric 4H-1,2,4-Triazoles to the Corresponding 1H-1,2,4-triazoles. Molecules 2001, 6, 481-495.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top