Regioselectivity in the Thermal Rearrangement of Unsymmetrical 4-Methyl-4H-1,2,4-triazoles to 1-Methyl-1H-1,2,4-triazoles

doi:10.3390/61200969

This article is

freely available
re-usable

Molecules 2001, 6(12), 969-978; doi:10.3390/61200969

Article

Regioselectivity in the Thermal Rearrangement of Unsymmetrical 4-Methyl-4H-1,2,4-triazoles to 1-Methyl-1H-1,2,4-triazoles

Odd R. Gautun and Per H.J. Carlsen*

Department of Chemistry, Norwegian University of Science and Technology, N-7491 Trondheim, Norway

* Author to whom correspondence should be addressed.

Received: 14 March 2001; in revised form: 26 October 2001 / Accepted: 26 October 2001 / Published: 30 November 2001

Download PDF Full-Text [51 KB, uploaded 25 November 2008 13:33 CET]

Abstract: The rearrangement of 4-methyl-3,5-diaryl-4H-1,2,4-triazoles to the corresponding 1-methyl-3,5-diaryl-1H-1,2,4-triazoles showed regioselectivity comparable to that observed for the alkylation of 3,5-diaryl-1H-1,2,4-triazoles. This lends support to a proposed mechanism for the rearrangement that involves consecutive nucleophilic displacements steps.

Keywords: Thermolysis; 1; 2; 4-triazole; Rearrangement; Regioselective

Article Statistics

Click here to load and display the download statistics.

Cite This Article

MDPI and ACS Style

Gautun, O.R.; Carlsen, P.H. Regioselectivity in the Thermal Rearrangement of Unsymmetrical 4-Methyl-4H-1,2,4-triazoles to 1-Methyl-1H-1,2,4-triazoles. Molecules 2001, 6, 969-978.

AMA Style

Gautun OR, Carlsen PH. Regioselectivity in the Thermal Rearrangement of Unsymmetrical 4-Methyl-4H-1,2,4-triazoles to 1-Methyl-1H-1,2,4-triazoles. Molecules. 2001; 6(12):969-978.

Chicago/Turabian Style

Gautun, Odd R.; Carlsen, Per H. 2001. "Regioselectivity in the Thermal Rearrangement of Unsymmetrical 4-Methyl-4H-1,2,4-triazoles to 1-Methyl-1H-1,2,4-triazoles." Molecules 6, no. 12: 969-978.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert